*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : QJ1897000 CHEMICAL NAME : 2-Naphthalenecarboxamide, 3-hydroxy-4-((2-methoxy-5-nitrophenyl)azo)-N-(3-nitro phenyl)- CAS REGISTRY NUMBER : 6471-49-4 LAST UPDATED : 199701 DATA ITEMS CITED : 9 MOLECULAR FORMULA : C24-H17-N5-O7 MOLECULAR WEIGHT : 487.46 WISWESSER LINE NOTATION : L66J BNUNR BO1 ENW& CQ DVMR CNW COMPOUND DESCRIPTOR : Tumorigen Mutagen SYNONYMS/TRADE NAMES : * Alkali Resistant Red Dark * Calcotone Red 3B * Carnation Red Toner B * C.I. 12355 * C.I. Pigment Red 157 * Congo Red R-138 * Fenalac Red FKB Extra * Malta Red X 2284 * 2-Naphthanilide, 3-hydroxy-4-((2-methoxy-5-nitrophenyl)azo)-3'-nitro- * Naphthol Red B * Naphthol Red B 20-7575 * Naphthol Red Deep 10459 * Naphthol Red D Toner 35-6001 * NCI-C60377 * Pigment Red 23 * Pigment Red BH * Rubescence Red MT-21 * Sanyo Fast Red 10B * Sapona Red Lake RL-6280 * Segnale Light Rubine RG * Textile Red WD-263 *** HEALTH HAZARD DATA *** ** OTHER MULTIPLE DOSE TOXICITY DATA ** TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 273 gm/kg/13W-C TOXIC EFFECTS : Blood - normocytic anemia REFERENCE : NTPTR* National Toxicology Program Technical Report Series. (Research Triangle Park, NC 27709) No.206- Volume(issue)/page/year: NTP-TR-411,1992 TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 102 gm/kg/17D-C TOXIC EFFECTS : Blood - pigmented or nucleated red blood cells Blood - changes in erythrocyte (RBC) count Nutritional and Gross Metabolic - weight loss or decreased weight gain REFERENCE : NTPTR* National Toxicology Program Technical Report Series. (Research Triangle Park, NC 27709) No.206- Volume(issue)/page/year: NTP-TR-411,1992 TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 136 gm/kg/13W-C TOXIC EFFECTS : Liver - changes in liver weight Endocrine - changes in thymus weight REFERENCE : NTPTR* National Toxicology Program Technical Report Series. (Research Triangle Park, NC 27709) No.206- Volume(issue)/page/year: NTP-TR-411,1992 ** MUTATION DATA ** TYPE OF TEST : Mutation in microorganisms TEST SYSTEM : Bacteria - Salmonella typhimurium DOSE/DURATION : 33 ug/plate REFERENCE : ENMUDM Environmental Mutagenesis. (New York, NY) V.1-9, 1979-87. For publisher information, see EMMUEG. Volume(issue)/page/year: 8(Suppl 7),1,1986 TYPE OF TEST : Mutation in microorganisms TEST SYSTEM : Bacteria - Salmonella typhimurium DOSE/DURATION : 10 ug/plate REFERENCE : NTPTR* National Toxicology Program Technical Report Series. (Research Triangle Park, NC 27709) No.206- Volume(issue)/page/year: NTP-TR-411,1992 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - M2113 No. of Facilities: 495 (estimated) No. of Industries: 16 No. of Occupations: 34 No. of Employees: 21254 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - M2113 No. of Facilities: 548 (estimated) No. of Industries: 11 No. of Occupations: 24 No. of Employees: 15233 (estimated) No. of Female Employees: 2716 (estimated) *** STATUS IN U.S. *** EPA TSCA Section 8(b) CHEMICAL INVENTORY NTP Carcinogenesis Studies (feed);equivocal:rat, no evidence:mouse NTPTR* National Toxicology Program Technical Report Series. (Research Triangle Park, NC 27709) No.206- Volume(issue)/page/year: NTP-TR-411,92 *** END OF RECORD ***