*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : QJ2900000
CHEMICAL NAME           : 1,2-Naphthalenediol, 4-(cyclohexylmethylamino)-,
                          diacetate (ester)
CAS REGISTRY NUMBER     : 121412-39-3
LAST UPDATED            : 199509
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C21-H25-N-O4
MOLECULAR WEIGHT        : 355.47
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * CGS 21595
   * 4-(Cyclohexylmethylamino)-1,2-naphthalenediol diacetate (ester)
 
                       *** HEALTH HAZARD DATA ***
 
                 ** OTHER MULTIPLE DOSE TOXICITY DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 45500 mg/kg/13W-I
TOXIC EFFECTS :
   Spinal Cord - demyelination
   Nutritional and Gross Metabolic - weight loss or decreased weight gain
   Related to Chronic Data - death
REFERENCE :
   VTPHAK Veterinary Pathology.  (Waverly Press, Inc., POB 64025, Baltimore, MD
   21264)  V.8-    1971-  Volume(issue)/page/year: 29,145,1992
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 50 gm/kg/10W-I
TOXIC EFFECTS :
   Peripheral Nerve and Sensation - recording from peripheral motor nerve
REFERENCE :
   ETPAEK Experimental and Toxicologic Pathology.  (Gustav Fischer Verlag Jena,
   Postfach 100537, D-07705 Jena, Germany)  V.44-    1992-
   Volume(issue)/page/year: 46,119,1994
 
                            *** END OF RECORD ***