*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : QJ5075000
CHEMICAL NAME : 1,4-Naphthalenediol, 2-methyl-
CAS REGISTRY NUMBER : 481-85-6
BEILSTEIN REFERENCE NO. : 1638194
REFERENCE : 4-06-00-06581 (Beilstein Handbook Reference)
LAST UPDATED : 199709
DATA ITEMS CITED : 3
MOLECULAR FORMULA : C11-H10-O2
MOLECULAR WEIGHT : 174.21
WISWESSER LINE NOTATION : L66J BQ C1 EQ
SYNONYMS/TRADE NAMES :
* Dihydrovitamin K3
* Menadiol
* 2-Methylhydronaphthoquinone
* Methylnaphthohydroquinone
* 2-Methyl-1,4-naphthohydroquinone
* 2-Methyl-1,4-naphthoquinol
* Reduced menadione
* Reduced vitamin K3
* Vitamin K3H2
*** HEALTH HAZARD DATA ***
** ACUTE TOXICITY DATA **
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 30 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams &
Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10-
Volume(issue)/page/year: 75,111,1942
TYPE OF TEST : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 400 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
CRSBAW Comptes Rendus des Seances de la Societe de Biologie et de Ses
Filiales. (SPPIF, B.P.22, F-41353 Vineuil, France) V.1- 1849-
Volume(issue)/page/year: 143,585,1949
TYPE OF TEST : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE : Subcutaneous
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 80 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity)
Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams &
Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10-
Volume(issue)/page/year: 71,210,1941
*** END OF RECORD ***