*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : QJ6430000
CHEMICAL NAME : 6,8-Naphthalenedisulfonic acid,
3,3'-((3,3'-dimethoxy-4,4'-biphenylene)bis(azo))bis(
5-amino-4-hydroxy-, tetrasodium salt
CAS REGISTRY NUMBER : 2610-05-1
LAST UPDATED : 199710
DATA ITEMS CITED : 13
MOLECULAR FORMULA : C34-H28-N6-O16-S4.4Na
MOLECULAR WEIGHT : 996.88
WISWESSER LINE NOTATION : L66J BZ CSWO ESWO JQ INUNR BO1 DR CO1 DNUN- IL66J BZ
CSWO ESWO JQ &-NA- 4
COMPOUND DESCRIPTOR : Mutagen
Reproductive Effector
SYNONYMS/TRADE NAMES :
* Airedale Blue FFD
* Amanil Sky Blue 6B
* Amanil Sky Blue FF
* Atlantic Resin Fast Blue
* Atlantic Sky Blue 6B
* Atlantic Sky Blue FF
* Atul Direct Sky Blue FB
* Azine Brilliant Blue 6B
* Azocard Blue 6B
* Belamine Sky Blue FF
* Benzanil Sky Blue FF
* Benzanil Supra Blue 2GN
* Benzo Brilliant Blue 6BS
* Brasilamina Sky Blue 6B
* Brilliant Benzo Blue 6BA-CF
* Calcodur Blue 6GFL
* Calcodur Resin Fast Blue
* Calcomine Sky Blue FF
* Chicago Blue 6B
* Chicago Sky Blue 6B
* Chloramine Sky Blue FF
* Chlorantine Fast Blue B5GL
* Chlorazol Sky Blue FF
* Chrome Leather Sky Blue
* C.I. 24410
* C.I. Direct Blue 1
* C.I. Direct Blue 1, tetrasodium salt
* Cresotine Blue 6B
* Diacotton Sky Blue 6B
* Diaphtamine Blue BS
* Diazine Sky Blue FF
* Diazol Pure Blue 6B
* Diphenyl Brilliant Blue FF
* Direct Blue 1
* Direct Blue 6B
* Direct Blue 6BS
* Direct Blue FF
* Direct Blue FFN
* Direct Bright Blue
* Direct Brilliant Blue FF
* Direct Brilliant Blue MFF
* Direct Brilliant Sky Blue 6B
* Direct Pure Blue 6B
* Direct Pure Blue FF
* Direct Sky Blue 6B
* Direct Sky Blue 6BS
* Direct Sky Blue FF
* Direct Sky Blue Green Shade
* Direct Sky Blue GS
* Enianil Brilliant Blue FF
* Fenamin Sky Blue 3F
* Fixanol Sky Blue FF
* Hispamin Sky Blue 6B
* Ink Blue 6B
* Japanol Brilliant Blue 6BKX
* Kayaku Direct Sky Blue 6B
* Lumicrease Blue 4GL
* Lumicrease Sky Blue 6GUL
* Mitsui Direct Brilliant Blue 6B
* Modr Prima 1
* Naphtamine Sky Blue DD
* NCI-C61109
* Niagara Sky Blue 6B
* Nsb6B
* Nyanza Sky Blue 6B
* Paper Blue 6B
* Paramine Sky Blue FF
* Phenamine Brilliant Blue 6B
* Pheno Sky Blue 6BX
* Pontamine Sky Blue
* Pontamine Sky Blue 6BX
* Pontamine Sky Blue 6BX Greenish
* Pontamine Sky Blue 6x
* Pure Sky Blue 6B
* Pyrazol Fast Brilliant Blue VP
* Shikiso Direct Sky Blue 6B
* Sirius Supra Blue 4G
* Sky Blue 6B
* Solar Blue 4GL
* Tertrodirect Blue FF
* Vegentine Blue CSW
* Vondacel Blue FF
*** HEALTH HAZARD DATA ***
** ACUTE TOXICITY DATA **
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 2260 mg/kg
TOXIC EFFECTS :
Cardiac - other changes
Lungs, Thorax, or Respiration - other changes
REFERENCE :
SCIEAS Science. (American Assoc. for the Advancement of Science, 1333 H
St., NW, Washington, DC 20005) V.1- 1895- Volume(issue)/page/year:
114,41,1951
** REPRODUCTIVE DATA **
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - rat
DOSE : 200 mg/kg
SEX/DURATION : female 8 day(s) after conception
TOXIC EFFECTS :
Reproductive - Specific Developmental Abnormalities - Central Nervous System
Reproductive - Specific Developmental Abnormalities - eye/ear
Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death,
e.g., stunted fetus)
REFERENCE :
PSEBAA Proceedings of the Society for Experimental Biology and Medicine.
(Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1903/04-
Volume(issue)/page/year: 127,215,1968
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - rat
DOSE : 140 mg/kg
SEX/DURATION : female 8 day(s) after conception
TOXIC EFFECTS :
Reproductive - Fertility - post-implantation mortality (e.g. dead and/or
resorbed implants per total number of implants)
REFERENCE :
PSEBAA Proceedings of the Society for Experimental Biology and Medicine.
(Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1903/04-
Volume(issue)/page/year: 127,215,1968
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - rat
DOSE : 200 mg/kg
SEX/DURATION : female 8 day(s) after conception
TOXIC EFFECTS :
Reproductive - Effects on Embryo or Fetus - other effects to embryo
REFERENCE :
TJADAB Teratology, The International Journal of Abnormal Development. (Alan
R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.1- 1968-
Volume(issue)/page/year: 2,85,1969
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - rat
DOSE : 100 mg/kg
SEX/DURATION : female 9 day(s) after conception
TOXIC EFFECTS :
Reproductive - Specific Developmental Abnormalities - eye/ear
REFERENCE :
RMEMDQ Revue Roumaine de Morphologie, d'Embryologie et de Physiologie, Serie
Morphologie et Embryologie. (Rompresfilatelia, POB 12-201, Bucharest,
Romania) V.21- 1975- Volume(issue)/page/year: 23,93,1977
** MUTATION DATA **
TYPE OF TEST : Mutation in microorganisms
TEST SYSTEM : Bacteria - Salmonella typhimurium
DOSE/DURATION : 100 nmol/plate
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE
Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 136,33,1984
TYPE OF TEST : Mutation in microorganisms
TEST SYSTEM : Bacteria - Salmonella typhimurium
DOSE/DURATION : 100 nmol/plate
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE
Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 97,103,1982
*** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***
NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
NOHS - National Occupational Hazard Survey (1974)
NOHS Hazard Code - M2162
No. of Facilities: 53 (estimated)
No. of Industries: 4
No. of Occupations: 6
No. of Employees: 1141 (estimated)
NOES - National Occupational Exposure Survey (1983)
NOES Hazard Code - M2162
No. of Facilities: 156 (estimated)
No. of Industries: 7
No. of Occupations: 14
No. of Employees: 10195 (estimated)
No. of Female Employees: 6491 (estimated)
*** STATUS IN U.S. ***
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA 8(a) PRELIMINARY ASSESSMENT INFORMATION, FINAL RULE
FEREAC Federal Register. (U.S. Government Printing Office, Supt. of
Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year:
47,26992,82
EPA TSCA Section 8(d) unpublished health/safety studies
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JUNE 1998
*** END OF RECORD ***