*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : QK3682000
CHEMICAL NAME           : 2-Naphthalenesulfonic acid,
                          1,2,3,4-tetrahydro-2-methyl-1,4-dioxo-, sodium salt
CAS REGISTRY NUMBER     : 130-37-0
LAST UPDATED            : 199806
DATA ITEMS CITED        : 8
MOLECULAR FORMULA       : C11-H9-O5-S.Na
MOLECULAR WEIGHT        : 276.25
COMPOUND DESCRIPTOR     : Mutagen
SYNONYMS/TRADE NAMES :
   * Golagen K
   * Hemoklot
   * Hetrogen K
   * Hetroge K premix
   * Hykinone
   * Ido-K
   * Kalzon
   * Kavitamin
   * Kavitan
   * Kawitan
   * Klotogen
   * Klotogen F
   * Klotogen F 16
   * Klotogen F 227
   * K-Trombina
   * Menadione sodium bisulfite
   * Menadione sodium hydrogen sulfite
   * Menaphthone sodium bisulfite
   * Menaphthone sodium bisulphite
   * MSBC
   * Sodium menadione bisulfite
   * 1,2,3,4-Tetrahydro-2-methyl-1,4-dioxo-2-naphthalenesulfonic acid sodium  
   salt
   * Vikasol
   * Vitamin K injection
   * Vitamin K3 sodium bisulfite
 
                       *** HEALTH HAZARD DATA ***
 
                 ** OTHER MULTIPLE DOSE TOXICITY DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 500 mg/kg/9D-I
TOXIC EFFECTS :
   Cardiac - other changes
   Nutritional and Gross Metabolic - weight loss or decreased weight gain
   Related to Chronic Data - death
REFERENCE :
   TXCYAC Toxicology.  (Elsevier Scientific Pub. Ireland, Ltd., POB 85,
   Limerick, Ireland) V.1-    1973-  Volume(issue)/page/year: 124,193,1997
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : DNA inhibition
TEST SYSTEM             : Human Leukocyte
DOSE/DURATION           : 25 umol/L
REFERENCE :
   BCPCA6 Biochemical Pharmacology.  (Pergamon Press Inc., Maxwell House,
   Fairview Park, Elmsford, NY 10523)  V.1-    1958-  Volume(issue)/page/year:
   41,1283,1991
 
TYPE OF TEST            : DNA inhibition
TEST SYSTEM             : Human Cells - not otherwise specified
DOSE/DURATION           : 50 umol/L
REFERENCE :
   BCPCA6 Biochemical Pharmacology.  (Pergamon Press Inc., Maxwell House,
   Fairview Park, Elmsford, NY 10523)  V.1-    1958-  Volume(issue)/page/year:
   41,1283,1991
 
TYPE OF TEST            : Mutation test systems - not otherwise specified
TEST SYSTEM             : Human Leukocyte
DOSE/DURATION           : 50 umol/L
REFERENCE :
   BCPCA6 Biochemical Pharmacology.  (Pergamon Press Inc., Maxwell House,
   Fairview Park, Elmsford, NY 10523)  V.1-    1958-  Volume(issue)/page/year:
   41,1283,1991
 
TYPE OF TEST            : Mutation test systems - not otherwise specified
TEST SYSTEM             : Human Cells - not otherwise specified
DOSE/DURATION           : 25 umol/L
REFERENCE :
   BCPCA6 Biochemical Pharmacology.  (Pergamon Press Inc., Maxwell House,
   Fairview Park, Elmsford, NY 10523)  V.1-    1958-  Volume(issue)/page/year:
   41,1283,1991

         *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
   NOHS - National Occupational Hazard Survey (1974)
     NOHS Hazard Code - 84777
       No. of Facilities: 21 (estimated)
       No. of Industries: 1
       No. of Occupations: 3
       No. of Employees: 705 (estimated)
   
   NOES - National Occupational Exposure Survey (1983)
     NOES Hazard Code - 84777
       No. of Facilities: 524 (estimated)
       No. of Industries: 2
       No. of Occupations: 3
       No. of Employees: 2658 (estimated)

                          *** STATUS IN U.S. ***
 
   EPA TSCA Section 8(b) CHEMICAL INVENTORY

 
                            *** END OF RECORD ***