*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : QK4250000
CHEMICAL NAME           : 2-Naphthalenol, 1-((4-(phenylazo)phenyl)azo)-
CAS REGISTRY NUMBER     : 85-86-9
BEILSTEIN REFERENCE NO. : 0931185
REFERENCE               : 4-16-00-00248 (Beilstein Handbook Reference)
LAST UPDATED            : 199701
DATA ITEMS CITED        : 12
MOLECULAR FORMULA       : C22-H16-N4-O
MOLECULAR WEIGHT        : 352.42
WISWESSER LINE NOTATION : L66J BNUNR DNUNR&& CQ
COMPOUND DESCRIPTOR     : Tumorigen
                          Mutagen
SYNONYMS/TRADE NAMES :
   * Atul Oil Red G
   * Benzeneazobenzeneazo-beta-naphthol
   * Brasilazina Oil Scarlet
   * Cerasin Red
   * Cerasinrot
   * Cerotinscharlach R
   * Certiqual Oil Red
   * Cerven rozpoustedlova 23
   * C.I. 23
   * C.I. 26100
   * C.I. Solvent Red 23
   * D & C Red No. 17
   * Fast Oil Scarlet III
   * Fat Red (bluish)
   * Fat Red HRR
   * Fat Red R
   * Fat Red RS
   * Fat Scarlet LB
   * Fat Soluble Red ZH
   * Grasal Brilliant Red G
   * Fettponceau G
   * Fettscharlach
   * Fettscharlach LB
   * Motirot 2R
   * Oil Red 6566
   * Oil Red AS
   * Oil Red 3G
   * Oil Scarlet G
   * Organol Red BS
   * Organol Scarlet
   * 1-((4-(Phenylazo)phenyl)azo)-2-naphthalenol
   * 1-((p-Phenylazo)phenyl)azo-2-naphthol
   * Pyronalrot B
   * 111440 Red
   * Red No. 225
   * Red ZH
   * Rouge cerasine
   * Scarlet B Fat Soluble
   * Schultz No. 31
   * Silotras Scarlet TB
   * Somalia Red III
   * Soudan III
   * Stearix Scarlet
   * Sudan III
   * Sudan III (G)
   * Sudan P III
   * Sudan Red III
   * Tetrazobenzene-beta-naphthol
   * Toney Red
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 250 mg/kg
TOXIC EFFECTS :
   Liver - hepatitis (hepatocellular necrosis), diffuse
   Liver - hepatitis (hepatocellular necrosis), zonal
   Liver - hepatitis, fibrous (cirrhosis, post-necrotic scarring)
REFERENCE :
   JPBAA7 Journal of Pathology and Bacteriology.  (London, UK)  V.1-96,
   1892-1968.  For publisher information, see JPTLAS. Volume(issue)/page/year:
   87,317,1964
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 1 gm/kg
TOXIC EFFECTS :
   Liver - hepatitis (hepatocellular necrosis), diffuse
   Liver - hepatitis (hepatocellular necrosis), zonal
   Liver - hepatitis, fibrous (cirrhosis, post-necrotic scarring)
REFERENCE :
   JPBAA7 Journal of Pathology and Bacteriology.  (London, UK)  V.1-96,
   1892-1968.  For publisher information, see JPTLAS. Volume(issue)/page/year:
   87,317,1964
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intrapleural
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 500 mg/kg
TOXIC EFFECTS :
   Liver - hepatitis (hepatocellular necrosis), diffuse
   Liver - hepatitis (hepatocellular necrosis), zonal
   Liver - hepatitis, fibrous (cirrhosis, post-necrotic scarring)
REFERENCE :
   JPBAA7 Journal of Pathology and Bacteriology.  (London, UK)  V.1-96,
   1892-1968.  For publisher information, see JPTLAS. Volume(issue)/page/year:
   87,317,1964
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : Phage inhibition capacity
TEST SYSTEM             : Bacteria - Escherichia coli
DOSE/DURATION           : 100 mmol/L
REFERENCE :
   MDMIAZ Medycyna Doswiadczalna i Mikrobiologia.  For English translation, see
   EXMMAV.  (Ars Polona, POB 1001, 00-068 Warsaw 1, Poland)  V.1-    1949-
   Volume(issue)/page/year: 31,11,1979
 
TYPE OF TEST            : Cytogenetic analysis
TEST SYSTEM             : Rodent - hamster Ovary
DOSE/DURATION           : 20 umol/L/5H (Continuous)
REFERENCE :
   ENMUDM Environmental Mutagenesis.  (New York, NY)  V.1-9, 1979-87.  For
   publisher information, see EMMUEG.  Volume(issue)/page/year: 1,27,1979

                              *** REVIEWS ***
 
   IARC Cancer Review:Animal Inadequate Evidence
   IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals
   to Man.  (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210)
   V.1-    1972-  Volume(issue)/page/year: 8,241,1975

   IARC Cancer Review:Human No Adequate Data
   IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals
   to Man.  (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210)
   V.1-    1972-  Volume(issue)/page/year: 8,241,1975

   IARC Cancer Review:Group 3
   IMSUDL IARC Monographs, Supplement.  (WHO Publications Centre USA, 49
   Sheridan Ave., Albany, NY 12210)  No.1-    1979-  Volume(issue)/page/year:
   7,56,1987

         *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
   NOHS - National Occupational Hazard Survey (1974)
     NOHS Hazard Code - 81045
       No. of Facilities: 650 (estimated)
       No. of Industries: 8
       No. of Occupations: 16
       No. of Employees: 5334 (estimated)
   
   NOES - National Occupational Exposure Survey (1983)
     NOES Hazard Code - 81045
       No. of Facilities: 437 (estimated)
       No. of Industries: 3
       No. of Occupations: 7
       No. of Employees: 7807 (estimated)
       No. of Female Employees: 5186 (estimated)

                          *** STATUS IN U.S. ***
 
   EPA GENETOX PROGRAM 1988, Inconclusive: B subtilis rec assay
   
   EPA TSCA Section 8(b) CHEMICAL INVENTORY

 
                            *** END OF RECORD ***