*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : QK4250000 CHEMICAL NAME : 2-Naphthalenol, 1-((4-(phenylazo)phenyl)azo)- CAS REGISTRY NUMBER : 85-86-9 BEILSTEIN REFERENCE NO. : 0931185 REFERENCE : 4-16-00-00248 (Beilstein Handbook Reference) LAST UPDATED : 199701 DATA ITEMS CITED : 12 MOLECULAR FORMULA : C22-H16-N4-O MOLECULAR WEIGHT : 352.42 WISWESSER LINE NOTATION : L66J BNUNR DNUNR&& CQ COMPOUND DESCRIPTOR : Tumorigen Mutagen SYNONYMS/TRADE NAMES : * Atul Oil Red G * Benzeneazobenzeneazo-beta-naphthol * Brasilazina Oil Scarlet * Cerasin Red * Cerasinrot * Cerotinscharlach R * Certiqual Oil Red * Cerven rozpoustedlova 23 * C.I. 23 * C.I. 26100 * C.I. Solvent Red 23 * D & C Red No. 17 * Fast Oil Scarlet III * Fat Red (bluish) * Fat Red HRR * Fat Red R * Fat Red RS * Fat Scarlet LB * Fat Soluble Red ZH * Grasal Brilliant Red G * Fettponceau G * Fettscharlach * Fettscharlach LB * Motirot 2R * Oil Red 6566 * Oil Red AS * Oil Red 3G * Oil Scarlet G * Organol Red BS * Organol Scarlet * 1-((4-(Phenylazo)phenyl)azo)-2-naphthalenol * 1-((p-Phenylazo)phenyl)azo-2-naphthol * Pyronalrot B * 111440 Red * Red No. 225 * Red ZH * Rouge cerasine * Scarlet B Fat Soluble * Schultz No. 31 * Silotras Scarlet TB * Somalia Red III * Soudan III * Stearix Scarlet * Sudan III * Sudan III (G) * Sudan P III * Sudan Red III * Tetrazobenzene-beta-naphthol * Toney Red *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - rabbit DOSE/DURATION : 250 mg/kg TOXIC EFFECTS : Liver - hepatitis (hepatocellular necrosis), diffuse Liver - hepatitis (hepatocellular necrosis), zonal Liver - hepatitis, fibrous (cirrhosis, post-necrotic scarring) REFERENCE : JPBAA7 Journal of Pathology and Bacteriology. (London, UK) V.1-96, 1892-1968. For publisher information, see JPTLAS. Volume(issue)/page/year: 87,317,1964 TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - rabbit DOSE/DURATION : 1 gm/kg TOXIC EFFECTS : Liver - hepatitis (hepatocellular necrosis), diffuse Liver - hepatitis (hepatocellular necrosis), zonal Liver - hepatitis, fibrous (cirrhosis, post-necrotic scarring) REFERENCE : JPBAA7 Journal of Pathology and Bacteriology. (London, UK) V.1-96, 1892-1968. For publisher information, see JPTLAS. Volume(issue)/page/year: 87,317,1964 TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Intrapleural SPECIES OBSERVED : Rodent - rabbit DOSE/DURATION : 500 mg/kg TOXIC EFFECTS : Liver - hepatitis (hepatocellular necrosis), diffuse Liver - hepatitis (hepatocellular necrosis), zonal Liver - hepatitis, fibrous (cirrhosis, post-necrotic scarring) REFERENCE : JPBAA7 Journal of Pathology and Bacteriology. (London, UK) V.1-96, 1892-1968. For publisher information, see JPTLAS. Volume(issue)/page/year: 87,317,1964 ** MUTATION DATA ** TYPE OF TEST : Phage inhibition capacity TEST SYSTEM : Bacteria - Escherichia coli DOSE/DURATION : 100 mmol/L REFERENCE : MDMIAZ Medycyna Doswiadczalna i Mikrobiologia. For English translation, see EXMMAV. (Ars Polona, POB 1001, 00-068 Warsaw 1, Poland) V.1- 1949- Volume(issue)/page/year: 31,11,1979 TYPE OF TEST : Cytogenetic analysis TEST SYSTEM : Rodent - hamster Ovary DOSE/DURATION : 20 umol/L/5H (Continuous) REFERENCE : ENMUDM Environmental Mutagenesis. (New York, NY) V.1-9, 1979-87. For publisher information, see EMMUEG. Volume(issue)/page/year: 1,27,1979 *** REVIEWS *** IARC Cancer Review:Animal Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 8,241,1975 IARC Cancer Review:Human No Adequate Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 8,241,1975 IARC Cancer Review:Group 3 IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,56,1987 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 81045 No. of Facilities: 650 (estimated) No. of Industries: 8 No. of Occupations: 16 No. of Employees: 5334 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 81045 No. of Facilities: 437 (estimated) No. of Industries: 3 No. of Occupations: 7 No. of Employees: 7807 (estimated) No. of Female Employees: 5186 (estimated) *** STATUS IN U.S. *** EPA GENETOX PROGRAM 1988, Inconclusive: B subtilis rec assay EPA TSCA Section 8(b) CHEMICAL INVENTORY *** END OF RECORD ***