*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : QK5960000
CHEMICAL NAME           : Naphthalimide, 4-methoxy-N-methyl-
CAS REGISTRY NUMBER     : 3271-05-4
OTHER CAS REGISTRY NOS. : 12224-26-9
BEILSTEIN REFERENCE NO. : 1534374
REFERENCE               : 5-21-13-00280 (Beilstein Handbook Reference)
LAST UPDATED            : 199712
DATA ITEMS CITED        : 4
MOLECULAR FORMULA       : C14-H11-N-O3
MOLECULAR WEIGHT        : 241.26
COMPOUND DESCRIPTOR     : Mutagen
SYNONYMS/TRADE NAMES :
   * 1H-Benz(de)isoquinoline-1,3(2H)-dione, 6-methoxy-2-methyl-
   * C.I. 56190
   * C.I. Fluorescent Brightener 162
   * Fluorescent Brightener 162
   * Fluorescent Brightening Agent 162
   * 4-Methoxy-N-methylnaphthalimide
   * N-Methyl-4-methoxynaphthalimide
   * Mikawhite AT
   * Mikawhite AT CONC
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 15 gm/kg
TOXIC EFFECTS :
   Sense Organs and Special Senses (Eye) - lacrimation
   Behavioral - somnolence (general depressed activity)
   Skin and Appendages - hair
REFERENCE :
   ESKHA5 Eisei Shikenjo Hokoku.  Bulletin of the Institute of Hygienic
   Sciences.  (Kokuritsu Eisei Shikenjo Kagaku, 18-1 Bushitsu Johobu,
   Setagaya-ku, Tokyo 158, Japan)  V.1-    1886-  Volume(issue)/page/year:
   (101),152,1983
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 7700 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   OKEHDW Osaka-furitsu Koshu Eisei Kenkyusho Kenkyu Hokoku, Koshu Eisei Hen.
   Research Reports of the Oaka Prefectural Institute of Public Health, Public
   Health Section.  (Osaka-furitsu Koshu Eisei Kenkyusho, 1-3-69 Nakamichi,
   Higashinari-ku, Osaka, 537, Japan)  No.3-    1966- Volume(issue)/page/year:
   20,95,1982
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : Body fluid assay
TEST SYSTEM             : Rodent - rat Bacteria - Salmonella typhimurium
DOSE/DURATION           : 12600 mg/kg/7D (Continuous)
REFERENCE :
   AECTCV Archives of Environmental Contamination and Toxicology.
   (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ
   070944)  V.1-    1973-  Volume(issue)/page/year: 16,119,1987

                          *** STATUS IN U.S. ***
 
   EPA TSCA Section 8(b) CHEMICAL INVENTORY

 
                            *** END OF RECORD ***