*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : QL5418800
CHEMICAL NAME           : 1-Naphthol,
                          1,2,3,4-tetrahydro-1-(p-fluorophenyl)-6-methoxy-2-phe
                          nyl-
CAS REGISTRY NUMBER     : 4310-62-7
BEILSTEIN REFERENCE NO. : 2016145
LAST UPDATED            : 199612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C23-H21-F-O2
MOLECULAR WEIGHT        : 348.44
WISWESSER LINE NOTATION : L66&TJ CO1 GQ GR DF& HR
COMPOUND DESCRIPTOR     : Reproductive Effector
SYNONYMS/TRADE NAMES :
   * 1-(p-Fluorophenyl)-6-methoxy-2-phenyl-1,2,3,4-tetrahydro-1-naphthol
   * 1,2,3,4-Tetrahydro-1-(p-fluorophenyl)-6-methoxy-2-phenyl-1-naphthol
 
                       *** HEALTH HAZARD DATA ***
 
                          ** REPRODUCTIVE DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 350 ug/kg
SEX/DURATION            : female 1 day(s) pre-mating
                          female 1-6 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Fertility - pre-implantation mortality (e.g. reduction in
   number of implants per female; total number of implants per corpora lutea)
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 9,172,1966
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 35 ug/kg
SEX/DURATION            : female 7 day(s) pre-mating
TOXIC EFFECTS :
   Reproductive - Maternal Effects - uterus, cervix, vagina
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 9,172,1966
 
                            *** END OF RECORD ***