*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : QL5775000
CHEMICAL NAME           : 2-Naphthol, 1-((4-(o-tolylazo)-o-tolyl)azo)-
CAS REGISTRY NUMBER     : 85-83-6
BEILSTEIN REFERENCE NO. : 0709018
REFERENCE               : 4-16-00-00249 (Beilstein Handbook Reference)
LAST UPDATED            : 199701
DATA ITEMS CITED        : 10
MOLECULAR FORMULA       : C24-H20-N4-O
MOLECULAR WEIGHT        : 380.48
WISWESSER LINE NOTATION : L66J BNUNR B1 DNUNR B1&& CQ
COMPOUND DESCRIPTOR     : Tumorigen
                          Drug
                          Mutagen
SYNONYMS/TRADE NAMES :
   * Biebrich Scarlet BPC
   * Biebrich Scarlet Red
   * Biebrich Scarlet R medicinal
   * Brasilazina Oil Red B
   * Calco Oil Red D
   * Candle Scarlet B
   * Candle Scarlet 2B
   * Candle Scarlet G
   * Ceres Red BB
   * Cerotine Ponceau 3B
   * Cerven rozpoustedlova 24
   * C.I. 258
   * C.I. 26105
   * C.I. Solvent Red 24
   * 2',3-Dimethyl-4-(2-hydroxynaphthylazo)azobenzene
   * Dispersol Red PP
   * Enial Red IV
   * Fast Oil Red B
   * Fast Red BB
   * Fat Ponceau R
   * Fat Red B
   * Fat Red 2B
   * Fat Red BB
   * Fat Red BS
   * Fat Red TS
   * Grasal Brilliant Red B
   * Grasan Brilliant Red B
   * Hidaco Oil Red
   * Lacquer Red V
   * Lacquer Red VS
   * Lipid Crimson
   * 1-((2-Methyl-4-((2-methylphenyl)azo)phenyl)azo)-2-naphthalenol
   * Oil Red IV
   * Oil Red 3
   * Oil Red 7
   * Oil Red 47
   * Oil Red 282
   * Oil Red A
   * Oil Red APT
   * Oil Red 2B
   * Oil Red 3B
   * Oil Red BB
   * Oil Red 4B
   * Oil Red BS
   * Oil Red D
   * Oil Red ED
   * Oil Red F
   * Oil Red GO
   * Oil Red PEL
   * Oil Red RC
   * Oil Red RR
   * Oil Red S
   * Oil Red TAX
   * Oil Red ZD
   * Oil Scarlet
   * Oil Scarlet 48
   * Oleal Red BB
   * Organol Red B
   * Orient Oil Red RR
   * Phenoplaste Organol Red B
   * Plastoresin Red F
   * Red 3R soluble IN grease
   * Resinol Red 2B
   * Rubrum scarlatinum
   * Resoform Red G
   * Sarlach R
   * Scarlet Red
   * Scarlet red, biebrich
   * Scarlet R (michaelis)
   * Scharlachrot
   * Schultz No. 541
   * Silotras Red T3B
   * Somalia Red IV
   * Stearix Red 4B
   * Stearix Red 4S
   * Sudan IV
   * Sudan P
   * Sudan Red IV
   * Sudan Red 4BA
   * Sudan Red BB
   * Sudan Red BBA
   * Tertrogras Red N
   * o-Tolueneazo-o-tolueneazo-beta-naphthol
   * o-Tolueneazo-o-toluene-beta-naphthol
   * o-Tolylazo-o-tolylazo-beta-naphthol
   * o-Tolylazo-o-tolylazo-2-naphthol
   * 1-(4-o-Tolylazo-o-tolylazo)-2-naphthol
   * Toyo Oil Red BB
   * Waxakol Red BL
   * Waxoline Red O
   * Waxoline Red OM
   * Waxoline Red OS
 
                       *** HEALTH HAZARD DATA ***
 
                          ** TUMORIGENIC DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 512 mg/kg/58W-C
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Tumorigenic - tumors at site of application
REFERENCE :
   GANNA2 Gann.  Japanese Journal of Cancer Research.  (Tokyo, Japan)  V.1-75,
   1907-84.  For publisher information, see JJCREP.  Volume(issue)/page/year:
   49,27,1958
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : Morphological transformation
TEST SYSTEM             : Rodent - hamster Embryo
DOSE/DURATION           : 100 mg/L
REFERENCE :
   AETODY Advances in Modern Environmental Toxicology.  (Senate Press, Inc.,
   P.O. Box 252, Princeton Junction, NJ 08550)  V.1-    1980-
   Volume(issue)/page/year: 1,241,1980

                              *** REVIEWS ***
 
   IARC Cancer Review:Animal Inadequate Evidence
   IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals
   to Man.  (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210)
   V.1-    1972-  Volume(issue)/page/year: 8,217,1975

   IARC Cancer Review:Human No Adequate Data
   IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals
   to Man.  (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210)
   V.1-    1972-  Volume(issue)/page/year: 8,217,1975

   IARC Cancer Review:Group 3
   IMSUDL IARC Monographs, Supplement.  (WHO Publications Centre USA, 49
   Sheridan Ave., Albany, NY 12210)  No.1-    1979-  Volume(issue)/page/year:
   7,56,1987

         *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
   NOHS - National Occupational Hazard Survey (1974)
     NOHS Hazard Code - A1356
       No. of Facilities: 212 (estimated)
       No. of Industries: 6
       No. of Occupations: 13
       No. of Employees: 2432 (estimated)
   
   NOES - National Occupational Exposure Survey (1983)
     NOES Hazard Code - A1356
       No. of Facilities: 1210 (estimated)
       No. of Industries: 15
       No. of Occupations: 23
       No. of Employees: 20219 (estimated)
       No. of Female Employees: 10256 (estimated)

                          *** STATUS IN U.S. ***
 
   EPA GENETOX PROGRAM 1988, Positive: Cell transform.-SA7/SHE
   
   EPA GENETOX PROGRAM 1988, Inconclusive: Histidine reversion-Ames test
   
   EPA TSCA Section 8(b) CHEMICAL INVENTORY

 
                            *** END OF RECORD ***