*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : QL6127200
CHEMICAL NAME           : 3H-Naphtho(2,1-b)pyran-2-carboxylic acid, 3-oxo-,
                          ethyl ester
CAS REGISTRY NUMBER     : 734-88-3
BEILSTEIN REFERENCE NO. : 0234987
REFERENCE               : 5-18-08-00444 (Beilstein Handbook Reference)
LAST UPDATED            : 199701
DATA ITEMS CITED        : 4
MOLECULAR FORMULA       : C16-H12-O4
MOLECULAR WEIGHT        : 268.28
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Belophar KLA
   * 5,6-Benzocumarin-3-carbonic acid ethyl ether
   * Compound 13-61
   * 5,6-Benzocoumarin-3-carboxylic acid ethyl ester
   * 3-Oxo-3H-naphtho(2,1-b)pyran-2-carboxylic acid ethyl ester
   * Optical bleach 13-61
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1580 mg/kg
TOXIC EFFECTS :
   Behavioral - altered sleep time (including change in righting reflex)
   Behavioral - excitement
   Behavioral - muscle contraction or spasticity
REFERENCE :
   GISAAA Gigiena i Sanitariya.  For English translation, see HYSAAV.  (V/O
   Mezhdunarodnaya Kniga, 113095 Moscow, USSR)  V.1-    1936-
   Volume(issue)/page/year: 49(1),85,1984
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 590 mg/kg
TOXIC EFFECTS :
   Behavioral - altered sleep time (including change in righting reflex)
   Behavioral - excitement
   Behavioral - muscle contraction or spasticity
REFERENCE :
   GISAAA Gigiena i Sanitariya.  For English translation, see HYSAAV.  (V/O
   Mezhdunarodnaya Kniga, 113095 Moscow, USSR)  V.1-    1936-
   Volume(issue)/page/year: 49(1),85,1984
 
                 ** OTHER MULTIPLE DOSE TOXICITY DATA **
 
TYPE OF TEST            : TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 180 mg/m3/4H/26W-I
TOXIC EFFECTS :
   Lungs, Thorax, or Respiration - other changes
   Liver - fatty liver degeneration
REFERENCE :
   GISAAA Gigiena i Sanitariya.  For English translation, see HYSAAV.  (V/O
   Mezhdunarodnaya Kniga, 113095 Moscow, USSR)  V.1-    1936-
   Volume(issue)/page/year: 46(7),81,1981

                          *** STATUS IN U.S. ***
 
   EPA TSCA Section 8(b) CHEMICAL INVENTORY

 
                            *** END OF RECORD ***