*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : QL7355000
CHEMICAL NAME           : 1,4-Naphthoquinone,
                          2-(1-aziridinyl)-5,6,7,8-tetrahydro-
CAS REGISTRY NUMBER     : 443-76-5
BEILSTEIN REFERENCE NO. : 0184025
REFERENCE               : 4-20-00-00013 (Beilstein Handbook Reference)
LAST UPDATED            : 199709
DATA ITEMS CITED        : 4
MOLECULAR FORMULA       : C12-H13-N-O2
MOLECULAR WEIGHT        : 203.26
WISWESSER LINE NOTATION : L66 BV EV&TJ C- BT3MTJ
COMPOUND DESCRIPTOR     : Mutagen
SYNONYMS/TRADE NAMES :
   * A 137
   * 2-Aethylenimino-5.6.7.8-tetrahydro-naphthochinon-1 4
   * 2-Ethyleneimino-5,6,7,8-tetrahydronaphthoquinone-1,4
   * 1,4-Naphthalenedione, 2-(1-aziridinyl)-5,6,7,8-tetrahydro-
 
                       *** HEALTH HAZARD DATA ***
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Escherichia coli
DOSE/DURATION           : 1 gm/L
REFERENCE :
   ATXKA8 Archiv fuer Toxikologie.  (Berlin, Fed. Rep. Ger.)  V.15-31, 1954-74.
    For publisher information, see ARTODN.  Volume(issue)/page/year: 28,93,1971
 
TYPE OF TEST            : Sex chromosome loss and nondisjunction
ROUTE OF EXPOSURE       : Oral
TEST SYSTEM             : Insect - Drosophila melanogaster
DOSE/DURATION           : 230 ppm
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 2,29,1965
 
TYPE OF TEST            : Cytogenetic analysis
TEST SYSTEM             : Human Leukocyte
DOSE/DURATION           : 1 umol/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 6,467,1968

                          *** STATUS IN U.S. ***
 
   EPA GENETOX PROGRAM 1988, Positive: D melanogaster Sex-linked lethal

 
                            *** END OF RECORD ***