*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : QL8485000 CHEMICAL NAME : 1,4-Naphthoquinone, 2-hydroxy-3-methyl- CAS REGISTRY NUMBER : 483-55-6 BEILSTEIN REFERENCE NO. : 1868473 REFERENCE : 4-08-00-02375 (Beilstein Handbook Reference) LAST UPDATED : 199709 DATA ITEMS CITED : 5 MOLECULAR FORMULA : C11-H8-O3 MOLECULAR WEIGHT : 188.19 WISWESSER LINE NOTATION : L66 BV EVJ CQ D1 COMPOUND DESCRIPTOR : Drug Mutagen SYNONYMS/TRADE NAMES : * 2-Hydroxy-3-methyl-1,4-naphthoquinone * 3-Hydroxy-2-methyl-1,4-naphthoquinone * 2-Methyl-3-hydroxy-1,4-naphthoquinone * 1,4-Naphthalenedione, 2-hydroxy-3-methyl- * Phthiocol * Phthiokol * Q 1212 *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 200 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : PSEBAA Proceedings of the Society for Experimental Biology and Medicine. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1903/04- Volume(issue)/page/year: 43,125,1940 TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 150 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : PSEBAA Proceedings of the Society for Experimental Biology and Medicine. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1903/04- Volume(issue)/page/year: 43,125,1940 TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Bird - chicken DOSE/DURATION : 100 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : PSEBAA Proceedings of the Society for Experimental Biology and Medicine. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1903/04- Volume(issue)/page/year: 43,125,1940 ** OTHER MULTIPLE DOSE TOXICITY DATA ** TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 3 gm/kg/30D-I TOXIC EFFECTS : Blood - pigmented or nucleated red blood cells Blood - changes in erythrocyte (RBC) count REFERENCE : PSEBAA Proceedings of the Society for Experimental Biology and Medicine. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1903/04- Volume(issue)/page/year: 43,125,1940 ** MUTATION DATA ** TYPE OF TEST : DNA inhibition TEST SYSTEM : Human HeLa cell DOSE/DURATION : 4 mmol/L REFERENCE : MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 93,447,1982 *** END OF RECORD ***