*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : QL9279000
CHEMICAL NAME           : 1,4-Naphthoquinone, 2-methyl-, sodium bisulfite,
                          trihydrate
CAS REGISTRY NUMBER     : 57414-02-5
LAST UPDATED            : 199109
DATA ITEMS CITED        : 4
MOLECULAR FORMULA       : C11-H9-O2.H-Na-O3-S.3H2-O
MOLECULAR WEIGHT        : 331.32
WISWESSER LINE NOTATION : L66 BV EVJ C1 &..H..S-O3 &-NA- &QH 3
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Menadion-natrium-bisulfit trihydrat
   * Menadion sodium bisulfite trihydrate
   * 2-Methyl-1,4-naphthochinon-natrium-bisulfit trihydrat
   * 2-Methyl-1,4-naphthoquinone sodiumbisulfite trihydrate
   * Vitamin K3-natrium-bisulfit trihydrat
   * Vitamin K3 sodium bisulfite trihydrate
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 2 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 18,676,1968
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 800 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 18,676,1968
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 2500 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 17,1339,1967
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 500 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 17,1339,1967
 
                            *** END OF RECORD ***