*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : QM3275000 CHEMICAL NAME : 2-Naphthylamine, 1-methoxy-, hydrochloride CAS REGISTRY NUMBER : 63020-03-1 LAST UPDATED : 199109 DATA ITEMS CITED : 4 MOLECULAR FORMULA : C11-H11-N-O.Cl-H MOLECULAR WEIGHT : 209.69 WISWESSER LINE NOTATION : L66J BO1 CZ &GH COMPOUND DESCRIPTOR : Tumorigen SYNONYMS/TRADE NAMES : * 1-Methoxy-2-aminonaphthalene * 1-Methoxy-2-naphthylamine hydrochloride * O-Methyl-2-amino-1-naphthol hydrochloride * Neosone D * Phenyl-beta-naphthalamine *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : LD - Lethal dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : >8437 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 18(5),48,1974 ** TUMORIGENIC DATA ** TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 12500 mg/kg/52W TOXIC EFFECTS : Tumorigenic - neoplastic by RTECS criteria Gastrointestinal - tumors REFERENCE : BJCAAI British Journal of Cancer. (Macmillan Press Ltd., Houndmills, Basingstoke, Hants. RG21 2XS, UK) V.1- 1947- Volume(issue)/page/year: 10,653,1956 TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Implant SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 50 mg/kg TOXIC EFFECTS : Tumorigenic - Carcinogenic by RTECS criteria Kidney, Ureter, Bladder - tumors REFERENCE : BJCAAI British Journal of Cancer. (Macmillan Press Ltd., Houndmills, Basingstoke, Hants. RG21 2XS, UK) V.1- 1947- Volume(issue)/page/year: 12,222,1958 *** REVIEWS *** TOXICOLOGY REVIEW ADCSAJ Advances in Chemistry Series. (American Chemical Soc., Distribution Office Dept. 223, POB 57136, West End Stn., Washington, DC 20037) No.1- 1950- Volume(issue)/page/year: 13,271,1970 *** END OF RECORD ***