*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : QN2840000
CHEMICAL NAME : 1,8-Naphthyridine-3-carboxylic acid,
1,4-dihydro-1-methyl-7-(2-(5-nitro-2-furyl)vinyl)-
4-oxo-, potassium salt
CAS REGISTRY NUMBER : 29676-95-7
LAST UPDATED : 198910
DATA ITEMS CITED : 3
MOLECULAR FORMULA : C16-H10-N3-O6.K
MOLECULAR WEIGHT : 379.39
COMPOUND DESCRIPTOR : Tumorigen
SYNONYMS/TRADE NAMES :
* NFN
*** HEALTH HAZARD DATA ***
** TUMORIGENIC DATA **
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 1411 mg/kg/14W-C
TOXIC EFFECTS :
Tumorigenic - Carcinogenic by RTECS criteria
Lungs, Thorax, or Respiration - tumors
Gastrointestinal - tumors
REFERENCE :
JJIND8 JNCI, Journal of the National Cancer Institute. (Washington, DC)
V.61-79, 1978-87. For publisher information, see JNCIEQ.
Volume(issue)/page/year: 69,1317,1982
TYPE OF TEST : TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 3150 mg/kg/25W-C
TOXIC EFFECTS :
Tumorigenic - Carcinogenic by RTECS criteria
Lungs, Thorax, or Respiration - tumors
Gastrointestinal - tumors
REFERENCE :
CIZAAZ Chiba Igaku Zasshi. Chiba Medical Journal. (Chiba Daigaku Igakkai,
1-8-1 Inohana, Chiba 280, Japan) V.50- 1974- Volume(issue)/page/year:
50,249,1974
TYPE OF TEST : TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 3276 mg/kg/26W-C
TOXIC EFFECTS :
Tumorigenic - Carcinogenic by RTECS criteria
Gastrointestinal - tumors
Blood - leukemia
REFERENCE :
CIGZAF Chiba Igakkai Zasshi. Journal of the Chiba Medical Society. (Chiba,
Japan) V.1-49, 1923-73. For publisher information, see CIZAAZ.
Volume(issue)/page/year: 50,249,1974
*** END OF RECORD ***