*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : QQ3450000
CHEMICAL NAME           : Neuraminidase
CAS REGISTRY NUMBER     : 9001-67-6
LAST UPDATED            : 199701
DATA ITEMS CITED        : 3
COMPOUND DESCRIPTOR     : Reproductive Effector
SYNONYMS/TRADE NAMES :
   * E.C. 3.2.1.18
   * alpha-Neuraminidase
   * Sialidase
 
                       *** HEALTH HAZARD DATA ***
 
                          ** REPRODUCTIVE DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 4000 iu/kg
SEX/DURATION            : female 4-6 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Fertility - post-implantation mortality (e.g. dead and/or
   resorbed implants per total number of implants)
   Reproductive - Fertility - litter size (e.g. # fetuses per litter; measured
   before birth)
REFERENCE :
   NMJOAA Nagoya Medical Journal.  (Nagoya City Univ. Medical School, Kawasumi,
   Mizuho-cho, Mizuho-ku, Nagoya 467, Japan)  V.1-    1953-
   Volume(issue)/page/year: 22,135,1977
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 2000 iu/kg
SEX/DURATION            : female 4 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Fertility - pre-implantation mortality (e.g. reduction in
   number of implants per female; total number of implants per corpora lutea)
REFERENCE :
   NMJOAA Nagoya Medical Journal.  (Nagoya City Univ. Medical School, Kawasumi,
   Mizuho-cho, Mizuho-ku, Nagoya 467, Japan)  V.1-    1953-
   Volume(issue)/page/year: 22,135,1977

                          *** STATUS IN U.S. ***
 
   EPA TSCA Section 8(b) CHEMICAL INVENTORY

 
                            *** END OF RECORD ***