*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : QL3700000
CHEMICAL NAME           : 2-Naphthol, 1-((2,4-dimethylpiperidino)methyl)-
CAS REGISTRY NUMBER     : 101781-39-9
LAST UPDATED            : 198806
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C18-H23-N-O
MOLECULAR WEIGHT        : 269.42
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 1-(2',4'-Dimethylpiperidinomethyl)-2-naphthol
   * Ro 3-0545
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 44 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Lungs, Thorax, or Respiration - respiratory depression
   Gastrointestinal - changes in structure or function of salivary glands
REFERENCE :
   BJPCAL British Journal of Pharmacology and Chemotherapy.  (London, UK)
   V.1-33, 1946-68.  For publisher information, see BJPCBM.
   Volume(issue)/page/year: 12,194,1957
 
                            *** END OF RECORD ***