*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : QT3005000
CHEMICAL NAME           : Nicotinium, 1'-methyl-, iodide
LAST UPDATED            : 198708
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C11-H17-N2.I
MOLECULAR WEIGHT        : 304.20
WISWESSER LINE NOTATION : T6NJ C- BT5NTJ A1 &I1
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Iodure de monomethylnicotinium
   * Nicotine, methiodide
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 995 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JMPCAS Journal of Medicinal and Pharmaceutical Chemistry.  (Washington, DC)
   V.1-5, 1959-62.  For publisher information, see JMCMAR.
   Volume(issue)/page/year: 2,449,1960
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 772 ug/kg
TOXIC EFFECTS :
   Vascular - BP elevation not characterized in autonomic section
REFERENCE :
   85IXA4 "Structure et Activite Pharmacodyanmique des Medicaments du Systeme
   Nerveux Vegetatif," Bovet, D., and F. Bovet-Nitti, New York, S. Karger, 1948
    Volume(issue)/page/year: -,586,1948
 
                            *** END OF RECORD ***