*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : QX1925000
CHEMICAL NAME : Nitrogen trifluoride
CAS REGISTRY NUMBER : 7783-54-2
LAST UPDATED : 199712
DATA ITEMS CITED : 28
MOLECULAR FORMULA : F3-N
MOLECULAR WEIGHT : 71.01
WISWESSER LINE NOTATION : N F3
SYNONYMS/TRADE NAMES :
* Nitrogen fluoride (NF3)
* Perfluoroammonia
* Nitrogen trifluoride
* Trifluoroammonia
*** HEALTH HAZARD DATA ***
** ACUTE TOXICITY DATA **
TYPE OF TEST : LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE : Inhalation
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 6700 ppm/1H
TOXIC EFFECTS :
Lungs, Thorax, or Respiration - dyspnea
Lungs, Thorax, or Respiration - cyanosis
Lungs, Thorax, or Respiration - respiratory stimulation
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E.
First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year:
26,1,1973
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 26 mg/kg
TOXIC EFFECTS :
Blood - methemoglobinemia-carboxyhemoglobin
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E.
First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year:
17,585,1970
TYPE OF TEST : LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE : Inhalation
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 2000 ppm/4H
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
34ZIAG "Toxicology of Drugs and Chemicals," Deichmann, W.B., New York,
Academic Press, Inc., 1969 Volume(issue)/page/year: -,427,1969
TYPE OF TEST : LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE : Inhalation
SPECIES OBSERVED : Mammal - dog
DOSE/DURATION : 9600 ppm/1H
TOXIC EFFECTS :
Lungs, Thorax, or Respiration - cyanosis
Blood - methemoglobinemia-carboxyhemoglobin
REFERENCE :
AMRL** Aerospace Medical Research Laboratory Report. (Aerospace Technical
Div., Air Force Systems Command, Wright-Patterson Air Force Base, OH 45433)
Volume(issue)/page/year: TR-69-84,1969
TYPE OF TEST : LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE : Inhalation
SPECIES OBSERVED : Primate - monkey
DOSE/DURATION : 7500 ppm/1H
TOXIC EFFECTS :
Lungs, Thorax, or Respiration - cyanosis
Blood - methemoglobinemia-carboxyhemoglobin
REFERENCE :
AMRL** Aerospace Medical Research Laboratory Report. (Aerospace Technical
Div., Air Force Systems Command, Wright-Patterson Air Force Base, OH 45433)
Volume(issue)/page/year: TR-69-84,1969
** OTHER MULTIPLE DOSE TOXICITY DATA **
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Inhalation
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 100 ppm/7H/19W-I
TOXIC EFFECTS :
Liver - fatty liver degeneration
Kidney, Ureter, Bladder - interstitial nephritis
Blood - changes in spleen
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E.
First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year:
4,770,1962
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : 85 gm/kg/29D-I
TOXIC EFFECTS :
Liver - hepatitis (hepatocellular necrosis), zonal
Kidney, Ureter, Bladder - other changes
Blood - changes in spleen
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E.
First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year:
4,770,1962
*** REVIEWS ***
ACGIH TLV-TWA 29 mg/m3 (10 ppm)
DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices
(BEIs) booklet issues by American Conference of Governmental Industrial
Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year:
TLV/BEI,1997
*** U.S. STANDARDS AND REGULATIONS ***
MSHA STANDARD-air:TWA 10 ppm (29 mg/m3)
DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices
(BEIs) booklet issues by American Conference of Governmental Industrial
Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year:
3,187,1971
OSHA PEL (Gen Indu):8H TWA 10 ppm (29 mg/m3)
CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt.
of Documents, Washington, DC 20402) Volume(issue)/page/year:
29,1910.1000,1994
OSHA PEL (Construc):8H TWA 10 ppm (29 mg/m3)
CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt.
of Documents, Washington, DC 20402) Volume(issue)/page/year:
29,1926.55,1994
OSHA PEL (Shipyard):8H TWA 10 ppm (29 mg/m3)
CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt.
of Documents, Washington, DC 20402) Volume(issue)/page/year:
29,1915.1000,1993
OSHA PEL (Fed Cont):8H TWA 10 ppm (29 mg/m3)
CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt.
of Documents, Washington, DC 20402) Volume(issue)/page/year:
41,50-204.50,1994
*** OCCUPATIONAL EXPOSURE LIMITS ***
OEL-AUSTRALIA:TWA 10 ppm (30 mg/m3) JAN 1993
OEL-BELGIUM:TWA 10 ppm (29 mg/m3) JAN 1993
OEL-DENMARK:TWA 10 ppm (29 mg/m3) JAN 1993
OEL-FINLAND:STEL 10 ppm (29 mg/m3) JAN 1993
OEL-FRANCE:TWA 10 ppm (30 mg/m3) JAN 1993
OEL-THE NETHERLANDS:TWA 10 ppm (29 mg/m3) JAN 1993
OEL-THE PHILIPPINES:TWA 10 ppm (29 mg/m3) JAN 1993
OEL-SWITZERLAND:TWA 10 ppm (30 mg/m3) JAN 1993
OEL-UNITED KINGDOM:TWA 10 ppm (30 mg/m3);STEL 15 ppm (45 mg/m3) JAN 1993
OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV
OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV
*** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***
NIOSH RECOMMENDED EXPOSURE LEVEL (REL) :
NIOSH REL TO NITROGEN TRIFLUORIDE-air:10H TWA 10 ppm
REFERENCE :
NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of
Health, Education, and Welfare, Reports and Memoranda.
Volume(issue)/page/year: DHHS #92-100,1992
NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
NOHS - National Occupational Hazard Survey (1974)
NOHS Hazard Code - 50885
No. of Facilities: 11 (estimated)
No. of Industries: 1
No. of Occupations: 3
No. of Employees: 357 (estimated)
NOES - National Occupational Exposure Survey (1983)
NOES Hazard Code - 50885
No. of Facilities: 7 (estimated)
No. of Industries: 1
No. of Occupations: 1
No. of Employees: 1096 (estimated)
No. of Female Employees: 140 (estimated)
*** STATUS IN U.S. ***
EPA TSCA Section 8(b) CHEMICAL INVENTORY
*** END OF RECORD ***