*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : RA5390000
CHEMICAL NAME           : 2,10,12,16,18-Nonadecapentanoic acid,
                          19-(3,6-dihydro-3-methyl-6-oxo-2H-pyran-2-yl)-17-ethy
                          l- 6-hydroxy-3,5,7,9,11,15-hexamethyl-8-oxo-
CAS REGISTRY NUMBER     : 87081-35-4
LAST UPDATED            : 199412
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C33-H48-O6
MOLECULAR WEIGHT        : 540.81
COMPOUND DESCRIPTOR     : Drug
                          Mutagen
SYNONYMS/TRADE NAMES :
   * Antibiotic CI 940
   * Antibiotic CL 1957A
   * CI-940
   * CL 1957A
   * Elactocin
   * Mantuamycin
   * PD 114720
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 3100 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85GDA2 "CRC Handbook of Antibiotic Compounds," Vols.1- ,  Berdy, J., Boca
   Raton, FL, CRC Press, 1980-  Volume(issue)/page/year: 13(3),204,1987
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : DNA inhibition
TEST SYSTEM             : Rodent - mouse Leukocyte
DOSE/DURATION           : 1 umol/L
REFERENCE :
   PAACA3 Proceedings of the American Association for Cancer Research. (Waverly
   Press, 428 E. Preston St., Baltimore, MD 21202)  V.1-    1954-
   Volume(issue)/page/year: 26,253,1985
 
TYPE OF TEST            : Mutation test systems - not otherwise specified
TEST SYSTEM             : Rodent - mouse Leukocyte
DOSE/DURATION           : 1 umol/L
REFERENCE :
   PAACA3 Proceedings of the American Association for Cancer Research. (Waverly
   Press, 428 E. Preston St., Baltimore, MD 21202)  V.1-    1954-
   Volume(issue)/page/year: 26,253,1985
 
                            *** END OF RECORD ***