*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : RB6880000
CHEMICAL NAME           : 2-Norbornanamine, N,2,3,3-tetramethyl-
CAS REGISTRY NUMBER     : 60-40-2
LAST UPDATED            : 199703
DATA ITEMS CITED        : 4
MOLECULAR FORMULA       : C11-H21-N
MOLECULAR WEIGHT        : 167.33
WISWESSER LINE NOTATION : L55 ATJ CM1 C1 D1 D1
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Inversine
   * Mecamilamina
   * Mecamine
   * Mecamylamine
   * Mekamine
   * 2-Methylaminoisocamphane
   * 3-Methylaminoisocamphane
   * 3-Methylaminoisokamfan
   * 3-beta-Methylamino-2,2,3-trimethylbicyclo(2.2.1)heptane
   * 2-Methylamino-2,3,3-trimethylnorborane
   * 2-Methylamino-2,3,3-trimethylnorbornane
   * N-Methyl-2-isocamphanamine
   * Mevasine
   * Revertina
   * N,2,3,3-Tetramethyl-2-norbornamine
   * N,2,3,3-Tetramethyl-2-norcamphanamine
   * Versamine
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 90 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   BCFAAI Bollettino Chimico Farmaceutico.  (Societa Editoriale Farmaceutica,
   Via Ausonio 12, 20123 Milan, Italy)  V.33-    1894- Volume(issue)/page/year:
   103,490,1964
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 40 mg/kg
TOXIC EFFECTS :
   Behavioral - sleep
REFERENCE :
   AITEAT Archivum Immunologiae et Therapiae Experimentalis. (Ars Polona, POB
   1001, 00-068 Warsaw 1, Poland)  V.10-    1962-  Volume(issue)/page/year:
   10,905,1962
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 37500 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   FATOAO Farmakologiya i Toksikologiya (Moscow).  For English translation, see
   PHTXA6 and RPTOAN. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.2-   
   1939-  Volume(issue)/page/year: 25,163,1962
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 11900 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   USXXAM United States Patent Document.  (U.S. Patent Office, Box 9,
   Washington, DC 20231)  Volume(issue)/page/year: #4168308
 
                            *** END OF RECORD ***