*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : RB7875000
CHEMICAL NAME           : 2-Norbornanone, 1,3,3-trimethyl-
CAS REGISTRY NUMBER     : 1195-79-5
BEILSTEIN REFERENCE NO. : 1861492
REFERENCE               : 2-07-00-00093 (Beilstein Handbook Reference)
LAST UPDATED            : 199701
DATA ITEMS CITED        : 6
MOLECULAR FORMULA       : C10-H16-O
MOLECULAR WEIGHT        : 152.26
WISWESSER LINE NOTATION : L55 A CVTJ B1 D1 D1
COMPOUND DESCRIPTOR     : Primary Irritant
SYNONYMS/TRADE NAMES :
   * Fenchon
   * Fenchone
   * 1,3,3-Trimethyl-2-norbornanone
   * 1,3,3-Trimethyl-2-norcamphanone
 
                       *** HEALTH HAZARD DATA ***
 
                      ** SKIN/EYE IRRITATION DATA **
 
TYPE OF TEST            : Standard Draize test
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 500 mg/24H
REACTION SEVERITY       : Mild
REFERENCE :
   FCTXAV Food and Cosmetics Toxicology.  (London, UK)  V.1-19, 1963-81.  For
   publisher information, see FCTOD7.  Volume(issue)/page/year: 14,769,1976
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 2100 mg/kg
TOXIC EFFECTS :
   Behavioral - general anesthetic
   Behavioral - convulsions or effect on seizure threshold
   Lungs, Thorax, or Respiration - respiratory depression
REFERENCE :
   AEXPBL Archiv fuer Experimentelle Pathologie und Pharmakologie.  (Leipzig,
   Ger. Dem. Rep.)  V.1-109, 1873-1925.  For publisher information, see NSAPCC.
    Volume(issue)/page/year: 50,199,1903
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Amphibian - frog
DOSE/DURATION           : 650 mg/kg
TOXIC EFFECTS :
   Peripheral Nerve and Sensation - spastic paralysis with or without sensory
   change
   Autonomic Nervous System - other (direct) parasympathomimetic
   Lungs, Thorax, or Respiration - respiratory depression
REFERENCE :
   AEXPBL Archiv fuer Experimentelle Pathologie und Pharmakologie.  (Leipzig,
   Ger. Dem. Rep.)  V.1-109, 1873-1925.  For publisher information, see NSAPCC.
    Volume(issue)/page/year: 50,199,1903

         *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
   NOHS - National Occupational Hazard Survey (1974)
     NOHS Hazard Code - M3913
       No. of Facilities: 83 (estimated)
       No. of Industries: 2
       No. of Occupations: 19
       No. of Employees: 2847 (estimated)
   
   NOES - National Occupational Exposure Survey (1983)
     NOES Hazard Code - M3913
       No. of Facilities: 905 (estimated)
       No. of Industries: 14
       No. of Occupations: 11
       No. of Employees: 12992 (estimated)
       No. of Female Employees: 6693 (estimated)

                          *** STATUS IN U.S. ***
 
   EPA TSCA Section 8(b) CHEMICAL INVENTORY

 
                            *** END OF RECORD ***