*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : RB7875000 CHEMICAL NAME : 2-Norbornanone, 1,3,3-trimethyl- CAS REGISTRY NUMBER : 1195-79-5 BEILSTEIN REFERENCE NO. : 1861492 REFERENCE : 2-07-00-00093 (Beilstein Handbook Reference) LAST UPDATED : 199701 DATA ITEMS CITED : 6 MOLECULAR FORMULA : C10-H16-O MOLECULAR WEIGHT : 152.26 WISWESSER LINE NOTATION : L55 A CVTJ B1 D1 D1 COMPOUND DESCRIPTOR : Primary Irritant SYNONYMS/TRADE NAMES : * Fenchon * Fenchone * 1,3,3-Trimethyl-2-norbornanone * 1,3,3-Trimethyl-2-norcamphanone *** HEALTH HAZARD DATA *** ** SKIN/EYE IRRITATION DATA ** TYPE OF TEST : Standard Draize test ROUTE OF EXPOSURE : Administration onto the skin SPECIES OBSERVED : Rodent - rabbit DOSE/DURATION : 500 mg/24H REACTION SEVERITY : Mild REFERENCE : FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 14,769,1976 ** ACUTE TOXICITY DATA ** TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 2100 mg/kg TOXIC EFFECTS : Behavioral - general anesthetic Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - respiratory depression REFERENCE : AEXPBL Archiv fuer Experimentelle Pathologie und Pharmakologie. (Leipzig, Ger. Dem. Rep.) V.1-109, 1873-1925. For publisher information, see NSAPCC. Volume(issue)/page/year: 50,199,1903 TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Amphibian - frog DOSE/DURATION : 650 mg/kg TOXIC EFFECTS : Peripheral Nerve and Sensation - spastic paralysis with or without sensory change Autonomic Nervous System - other (direct) parasympathomimetic Lungs, Thorax, or Respiration - respiratory depression REFERENCE : AEXPBL Archiv fuer Experimentelle Pathologie und Pharmakologie. (Leipzig, Ger. Dem. Rep.) V.1-109, 1873-1925. For publisher information, see NSAPCC. Volume(issue)/page/year: 50,199,1903 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - M3913 No. of Facilities: 83 (estimated) No. of Industries: 2 No. of Occupations: 19 No. of Employees: 2847 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - M3913 No. of Facilities: 905 (estimated) No. of Industries: 14 No. of Occupations: 11 No. of Employees: 12992 (estimated) No. of Female Employees: 6693 (estimated) *** STATUS IN U.S. *** EPA TSCA Section 8(b) CHEMICAL INVENTORY *** END OF RECORD ***