*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : RC8961500
CHEMICAL NAME : 19-Nor-17-alpha-pregn-4-en-20-yne-3-beta,17-diol
CAS REGISTRY NUMBER : 1231-93-2
LAST UPDATED : 199512
DATA ITEMS CITED : 3
MOLECULAR FORMULA : C20-H28-O2
MOLECULAR WEIGHT : 300.48
WISWESSER LINE NOTATION : L E5 B666 MUTJ E1 FQ F1UU1 OQ
COMPOUND DESCRIPTOR : Reproductive Effector
Human
Hormone
SYNONYMS/TRADE NAMES :
* Ethinodiol
* Ethynodiol
* 17-alpha-Ethynyl-19-norandrost-4-ene-3-beta,17-beta-diol
* 19-Norpregn-4-en-20-yne-3,17-diol, (3-beta,17-alpha)-
*** HEALTH HAZARD DATA ***
** REPRODUCTIVE DATA **
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Unreported
SPECIES OBSERVED : Human - woman
DOSE : 12 mg/kg
SEX/DURATION : female 6-20 week(s) after conception
TOXIC EFFECTS :
Reproductive - Effects on Newborn - behavioral
REFERENCE :
SCIEAS Science. (American Assoc. for the Advancement of Science, 1333 H
St., NW, Washington, DC 20005) V.1- 1895- Volume(issue)/page/year:
211,1171,1981
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE : 100 mg/kg
SEX/DURATION : female 17-20 day(s) after conception
TOXIC EFFECTS :
Reproductive - Specific Developmental Abnormalities - urogenital system
REFERENCE :
ECJPAE Endocrinologia Japonica. (Japan Pub. Trading Co., Ltd., POB 5030,
Tokyo International, Tokyo, Japan) V.1- 1954- Volume(issue)/page/year:
24,77,1977
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Subcutaneous
SPECIES OBSERVED : Rodent - rabbit
DOSE : 200 ug/kg
SEX/DURATION : female 1 day(s) pre-mating
TOXIC EFFECTS :
Reproductive - Fertility - other measures of fertility
REFERENCE :
85GRAA "The Control of Fertility," Pincus, G., New York, Academic Press,
1965 Volume(issue)/page/year: -,57,1965
*** END OF RECORD ***