*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : RD3901000
CHEMICAL NAME           : Notonesomycin A, disodium salt
SUBSTANCE DEFINITION :
   A macrolide antibiotic containing a sulfonate group, a malonate moiety, two
   desoxy sugars and a 1,3,4-trisubstituted benzene system in the molecule
REFERENCE :
   JANTAJ Journal of Antibiotics.  (Japan Antibiotics Research Assoc., 2-20-8
   Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan)  V.2-5, 1948-52;  V.21- 1968-
   Volume(issue)/page/year: 39,502,1986
LAST UPDATED            : 199506
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C68-H109-N-O30-S.2Na
MOLECULAR WEIGHT        : 1498.82
COMPOUND DESCRIPTOR     : Drug
                          Natural Product
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 250 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JANTAJ Journal of Antibiotics.  (Japan Antibiotics Research Assoc., 2-20-8
   Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan)  V.2-5, 1948-52;  V.21- 1968-
   Volume(issue)/page/year: 39,502,1986
 
                            *** END OF RECORD ***