*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : RF0750000
CHEMICAL NAME           : Nuclease, deoxyribo-
CAS REGISTRY NUMBER     : 9003-98-9
LAST UPDATED            : 199701
DATA ITEMS CITED        : 7
COMPOUND DESCRIPTOR     : Mutagen
SYNONYMS/TRADE NAMES :
   * Alkaline deoxyribonuclease
   * Alkaline dnase
   * Deoxyribonuclease
   * Deoxyribonuclease A
   * Deoxyribonuclease I
   * Deoxyribonuclease (pancreatic)
   * Deoxyribonucleic phosphatase
   * Desoxyribonuclease
   * Dnaase
   * DNA depolymerase
   * DNA endonuclease
   * DNA nuclease
   * Dnasw
   * Dnase I
   * Dornase
   * Dornava
   * Dornavac
   * E.C. 3.1.4.5
   * Endodeoxyribonuclease I
   * Escherichia coli endonuclease I
   * Pancreatic deoxyribonuclease
   * Pancreatic dornase
 
                       *** HEALTH HAZARD DATA ***
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : Cytogenetic analysis
TEST SYSTEM             : Insect - Drosophila melanogaster Cells - not
                          otherwise specified
DOSE/DURATION           : 1 gm/L
REFERENCE :
   NULSAK Nucleus (Calcutta).  (Dr. A.K. Sharma, Centre of Advanced Studies in
   Cell and Chromosome Research, Calcutta, 35 Baliygunge Circular Rd., Calcutta
   700 019, India)  V.1-    1958-  Volume(issue)/page/year: 2,85,1959
 
TYPE OF TEST            : Cytogenetic analysis
TEST SYSTEM             : Insect - grasshopper Cells - not otherwise specified
DOSE/DURATION           : 1 gm/L
REFERENCE :
   NULSAK Nucleus (Calcutta).  (Dr. A.K. Sharma, Centre of Advanced Studies in
   Cell and Chromosome Research, Calcutta, 35 Baliygunge Circular Rd., Calcutta
   700 019, India)  V.1-    1958-  Volume(issue)/page/year: 2,85,1959
 
TYPE OF TEST            : DNA damage
TEST SYSTEM             : Rodent - hamster Fibroblast
DOSE/DURATION           : 5000 ppm
REFERENCE :
   SFCRAO Collection of Papers Presented at the Annual Symposium on Fundamental
   Cancer Research. (Baltimore, MD)  V.1-29, 1946-76.  For publisher
   information, see AFCPDR.  Volume(issue)/page/year: 23,346,1970
 
TYPE OF TEST            : Sister chromatid exchange
TEST SYSTEM             : Rodent - hamster Ovary
DOSE/DURATION           : 2500 units
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 307,315,1994

         *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
   NOHS - National Occupational Hazard Survey (1974)
     NOHS Hazard Code - 81370
       No. of Facilities: 181 (estimated)
       No. of Industries: 1
       No. of Occupations: 5
       No. of Employees: 1471 (estimated)
   
   NOES - National Occupational Exposure Survey (1983)
     NOES Hazard Code - 81370
       No. of Facilities: 116 (estimated)
       No. of Industries: 1
       No. of Occupations: 5
       No. of Employees: 8763 (estimated)
       No. of Female Employees: 8131 (estimated)

                          *** STATUS IN U.S. ***
 
   EPA TSCA Section 8(b) CHEMICAL INVENTORY

 
                            *** END OF RECORD ***