*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : RG2010000
CHEMICAL NAME           : 1-Octadecanol
CAS REGISTRY NUMBER     : 112-92-5
BEILSTEIN REFERENCE NO. : 1362907
REFERENCE               : 4-01-00-01888 (Beilstein Handbook Reference)
LAST UPDATED            : 199710
DATA ITEMS CITED        : 8
MOLECULAR FORMULA       : C18-H38-O
MOLECULAR WEIGHT        : 270.56
WISWESSER LINE NOTATION : Q18
COMPOUND DESCRIPTOR     : Tumorigen
                          Primary Irritant
SYNONYMS/TRADE NAMES :
   * Adol 68
   * Alfol 18
   * Atalco S
   * CO-1895
   * CO-1897
   * Crodacol-S
   * Decyl octyl alcohol
   * Dytol E-46
   * Lorol 28
   * Octadecanol
   * n-Octadecanol
   * Octadecyl alcohol
   * n-Octadecyl alcohol
   * Polaax
   * Sipol S
   * Siponol S
   * Stearol
   * Stearyl alcohol
   * Steraffine
   * USP XIII stearyl alcohol
 
                       *** HEALTH HAZARD DATA ***
 
                      ** SKIN/EYE IRRITATION DATA **
 
TYPE OF TEST            : Standard Draize test
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 500 mg/24H
REACTION SEVERITY       : Mild
REFERENCE :
   JACTDZ Journal of the American College of Toxicology.  (Mary Ann Liebert,
   Inc., 1651 Third Ave., New York, NY 10128)  V.1-12, 1982-1993. Discontinued.
    Volume(issue)/page/year: 4(5),1,1985
 
TYPE OF TEST            : Standard Draize test
ROUTE OF EXPOSURE       : Administration into the eye
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 100 mg/24H
REACTION SEVERITY       : Mild
REFERENCE :
   JACTDZ Journal of the American College of Toxicology.  (Mary Ann Liebert,
   Inc., 1651 Third Ave., New York, NY 10128)  V.1-12, 1982-1993. Discontinued.
    Volume(issue)/page/year: 4(5),1,1985
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 20 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   37ASAA "Kirk-Othmer Encyclopedia of Chemical Technology," 3rd ed., Grayson,
   M., and D. Eckroth, eds., New York, John Wiley & Sons, Inc., 1978
   Volume(issue)/page/year: 1,722,1978
 
                          ** TUMORIGENIC DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Implant
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1000 mg/kg
TOXIC EFFECTS :
   Tumorigenic - neoplastic by RTECS criteria
   Kidney, Ureter, Bladder - tumors
REFERENCE :
   CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
   Sts., Philadelphia, PA 19106)  V.1-    1941-  Volume(issue)/page/year:
   26,105,1966

         *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
   NOHS - National Occupational Hazard Survey (1974)
     NOHS Hazard Code - 80705
       No. of Facilities: 3948 (estimated)
       No. of Industries: 37
       No. of Occupations: 44
       No. of Employees: 60590 (estimated)
   
   NOES - National Occupational Exposure Survey (1983)
     NOES Hazard Code - 80705
       No. of Facilities: 22262 (estimated)
       No. of Industries: 177
       No. of Occupations: 127
       No. of Employees: 508141 (estimated)
       No. of Female Employees: 181509 (estimated)

                          *** STATUS IN U.S. ***
 
   EPA TSCA Section 8(b) CHEMICAL INVENTORY
   
   EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JUNE 1998

 
                            *** END OF RECORD ***