*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : RH3400000
CHEMICAL NAME           : 6-Octen-1-ol, 3,7-dimethyl-
CAS REGISTRY NUMBER     : 106-22-9
BEILSTEIN REFERENCE NO. : 1721507
REFERENCE               : 4-01-00-02188 (Beilstein Handbook Reference)
LAST UPDATED            : 199701
DATA ITEMS CITED        : 10
MOLECULAR FORMULA       : C10-H20-O
MOLECULAR WEIGHT        : 156.30
WISWESSER LINE NOTATION : Q2Y1&3UY1&1
COMPOUND DESCRIPTOR     : Natural Product
                          Primary Irritant
SYNONYMS/TRADE NAMES :
   * Cephrol
   * Citronellol
   * 2,6-Dimethyl-2-octen-8-ol
   * 3,7-Dimethyl-6-octen-1-ol
   * Rhodinol
   * Rodinol
 
                       *** HEALTH HAZARD DATA ***
 
                      ** SKIN/EYE IRRITATION DATA **
 
TYPE OF TEST            : Standard Draize test
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Human - man
DOSE/DURATION           : 16 mg/48H
REACTION SEVERITY       : Moderate
REFERENCE :
   CTOIDG Cosmetics and Toiletries.  (Allured Pub. Corp., POB 318, Wheaton, IL
   60189)  V.91-    1976-  Volume(issue)/page/year: 94(8),41,1979
 
TYPE OF TEST            : Standard Draize test
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 100 mg/24H
REACTION SEVERITY       : Severe
REFERENCE :
   CTOIDG Cosmetics and Toiletries.  (Allured Pub. Corp., POB 318, Wheaton, IL
   60189)  V.91-    1976-  Volume(issue)/page/year: 94(8),41,1979
 
TYPE OF TEST            : Standard Draize test
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - guinea pig
DOSE/DURATION           : 100 mg/24H
REACTION SEVERITY       : Severe
REFERENCE :
   CTOIDG Cosmetics and Toiletries.  (Allured Pub. Corp., POB 318, Wheaton, IL
   60189)  V.91-    1976-  Volume(issue)/page/year: 94(8),41,1979
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 3450 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   FCTXAV Food and Cosmetics Toxicology.  (London, UK)  V.1-19, 1963-81.  For
   publisher information, see FCTOD7.  Volume(issue)/page/year: 13,757,1975
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 880 mg/kg
TOXIC EFFECTS :
   Peripheral Nerve and Sensation - spastic paralysis with or without sensory
   change
REFERENCE :
   SIZSAR Sapporo Igaku Zasshi.  Sapporo Medical Journal.  (Sapporo Igaku
   Daigaku, Nishi-17-chome, Minami-1-jo, Chuo-ku, Sapporo 060, Japan)  V.3-
   1952-  Volume(issue)/page/year: 3,73,1952
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intramuscular
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 4 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JSICAZ Journal of Scientific and Industrial Research, Section C: Biological
   Sciences.  (New Delhi, India)  V.14-21, 1955-62.  For publisher information,
   see IJEBA6.  Volume(issue)/page/year: 21,342,1962
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 2650 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   FCTXAV Food and Cosmetics Toxicology.  (London, UK)  V.1-19, 1963-81.  For
   publisher information, see FCTOD7.  Volume(issue)/page/year: 13,757,1975

         *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
   NOHS - National Occupational Hazard Survey (1974)
     NOHS Hazard Code - A1604
       No. of Facilities: 63 (estimated)
       No. of Industries: 4
       No. of Occupations: 35
       No. of Employees: 7418 (estimated)
   
   NOES - National Occupational Exposure Survey (1983)
     NOES Hazard Code - A1604
       No. of Facilities: 8621 (estimated)
       No. of Industries: 62
       No. of Occupations: 83
       No. of Employees: 163706 (estimated)
       No. of Female Employees: 87309 (estimated)

                          *** STATUS IN U.S. ***
 
   EPA TSCA Section 8(b) CHEMICAL INVENTORY

 
                            *** END OF RECORD ***