*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : RH7122000
CHEMICAL NAME : Octylamine, N-methyl-N-nitroso-
CAS REGISTRY NUMBER : 34423-54-6
BEILSTEIN REFERENCE NO. : 4372422
LAST UPDATED : 199612
DATA ITEMS CITED : 3
MOLECULAR FORMULA : C9-H20-N2-O
MOLECULAR WEIGHT : 172.31
WISWESSER LINE NOTATION : ONN8&1
COMPOUND DESCRIPTOR : Tumorigen
Mutagen
SYNONYMS/TRADE NAMES :
* N-Methyl-N-nitrosooctylamine
* Nitrosomethyl-n-octylamine
* Nitroso-N-methyl-n-octylamine
* N-Nitrosomethyl-n-octylamine
* 1-Octylamine, N-methyl-N-nitroso-
*** HEALTH HAZARD DATA ***
** TUMORIGENIC DATA **
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 4480 mg/kg/43W-C
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria
Liver - tumors
Kidney, Ureter, Bladder - tumors
REFERENCE :
CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year:
41,1288,1981
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - hamster
DOSE/DURATION : 2888 mg/kg/40W-I
TOXIC EFFECTS :
Tumorigenic - neoplastic by RTECS criteria
Liver - tumors
Gastrointestinal - tumors
REFERENCE :
CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year:
48,6648,1988
** MUTATION DATA **
TYPE OF TEST : Mutation in microorganisms
TEST SYSTEM : Bacteria - Salmonella typhimurium
DOSE/DURATION : 50 ug/plate
REFERENCE :
TCMUD8 Teratogenesis, Carcinogenesis, and Mutagenesis. (Alan R. Liss, Inc.,
41 E. 11th St., New York, NY 10003) V.1- 1980- Volume(issue)/page/year:
1,295,1980
*** END OF RECORD ***