*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : RJ3691950 CHEMICAL NAME : Oils, heavy fuel #6 SUBSTANCE DEFINITION : #6 fuel oil, API gravity 5.2/1.2% S REFERENCE : 52MLA2 "Toxicology of Petroleum Hydrocarbons, Proceedings of the Symposium, 1st, 1982," MacFarland, H.N., et al., eds., Washington, DC, American Petroleum Institute, 1983 LAST UPDATED : 199609 DATA ITEMS CITED : 5 COMPOUND DESCRIPTOR : Primary Irritant SYNONYMS/TRADE NAMES : * #6 Heavy fuel oils * No.6 Home heating oil *** HEALTH HAZARD DATA *** ** SKIN/EYE IRRITATION DATA ** TYPE OF TEST : Standard Draize test ROUTE OF EXPOSURE : Administration onto the skin SPECIES OBSERVED : Rodent - rabbit DOSE/DURATION : 500 mg/24H REACTION SEVERITY : Mild REFERENCE : 52MLA2 "Toxicology of Petroleum Hydrocarbons, Proceedings of the Symposium, 1st, 1982," MacFarland, H.N., et al., eds., Washington, DC, American Petroleum Institute, 1983 Volume(issue)/page/year: 1,1,1983 TYPE OF TEST : Standard Draize test ROUTE OF EXPOSURE : Administration into the eye SPECIES OBSERVED : Rodent - rabbit DOSE/DURATION : 100 mg/30S REACTION SEVERITY : Mild REFERENCE : 52MLA2 "Toxicology of Petroleum Hydrocarbons, Proceedings of the Symposium, 1st, 1982," MacFarland, H.N., et al., eds., Washington, DC, American Petroleum Institute, 1983 Volume(issue)/page/year: 1,1,1983 ** ACUTE TOXICITY DATA ** TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 5100 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : AETODY Advances in Modern Environmental Toxicology. (Senate Press, Inc., P.O. Box 252, Princeton Junction, NJ 08550) V.1- 1980- Volume(issue)/page/year: 6,1,1984 TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Administration onto the skin SPECIES OBSERVED : Rodent - rabbit DOSE/DURATION : 5 gm/kg TOXIC EFFECTS : Gastrointestinal - hypermotility, diarrhea Gastrointestinal - other changes REFERENCE : 52MLA2 "Toxicology of Petroleum Hydrocarbons, Proceedings of the Symposium, 1st, 1982," MacFarland, H.N., et al., eds., Washington, DC, American Petroleum Institute, 1983 Volume(issue)/page/year: 1,1,1983 ** OTHER MULTIPLE DOSE TOXICITY DATA ** TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Administration onto the skin SPECIES OBSERVED : Rodent - rabbit DOSE/DURATION : 20 mL/kg/12D-C TOXIC EFFECTS : Skin and Appendages - dermatitis, irritative (after systemic exposure) Nutritional and Gross Metabolic - weight loss or decreased weight gain Related to Chronic Data - death REFERENCE : 52MLA2 "Toxicology of Petroleum Hydrocarbons, Proceedings of the Symposium, 1st, 1982," MacFarland, H.N., et al., eds., Washington, DC, American Petroleum Institute, 1983 Volume(issue)/page/year: 1,1,1983 *** END OF RECORD ***