*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : RK0177560
CHEMICAL NAME           : Olean-12-ene-28,29-dioic acid,
                          2,23-dihydroxy-3-(beta-D-xylopyranosyloxy)-,
                          29-methyl ester, (2-beta,3-beta,4-alpha,20-beta)-
CAS REGISTRY NUMBER     : 60820-94-2
LAST UPDATED            : 198706
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C36-H56-O11
MOLECULAR WEIGHT        : 664.92
COMPOUND DESCRIPTOR     : Drug
                          Natural Product
SYNONYMS/TRADE NAMES :
   * Phytolaccasaponin B
   * Phytolaccoside B
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 10800 ug/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Lungs, Thorax, or Respiration - respiratory depression
   Nutritional and Gross Metabolic - weight loss or decreased weight gain
REFERENCE :
   SYHJAM Saengyak Hakhoechi.  Journal of the Society of Pharmacognosy. (Hanguk
   Saengyak Hakhoe, c/o Natural Products Institute, Seoul National Univ., 28
   Yunkeon-Dong, Chong-ro-ku, Seoul 110, Korea)  1970- Volume(issue)/page/year:
   10,73,1979
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 4500 ug/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Lungs, Thorax, or Respiration - respiratory depression
   Nutritional and Gross Metabolic - weight loss or decreased weight gain
REFERENCE :
   SYHJAM Saengyak Hakhoechi.  Journal of the Society of Pharmacognosy. (Hanguk
   Saengyak Hakhoe, c/o Natural Products Institute, Seoul National Univ., 28
   Yunkeon-Dong, Chong-ro-ku, Seoul 110, Korea)  1970- Volume(issue)/page/year:
   10,73,1979
 
                            *** END OF RECORD ***