*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : RM2981540
CHEMICAL NAME           : Ornithine, N(sup 5)-carbamoyl-, L-, and sodium
                          nitrite (2:1)
LAST UPDATED            : 198910
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C6-H13-N3-O3.1/2N-Na-O2
MOLECULAR WEIGHT        : 239.68
COMPOUND DESCRIPTOR     : Tumorigen
                          Reproductive Effector
SYNONYMS/TRADE NAMES :
   * L-Citrulline and sodium nitrite (2:1)
   * Sodium nitrite and L-citrulline (1:2)
 
                       *** HEALTH HAZARD DATA ***
 
                          ** TUMORIGENIC DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1650 mg/kg
                          female 13-23 day(s) after conception
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Reproductive - Tumorigenic effects - transplacental tumorigenesis
   Kidney, Ureter, Bladder - Kidney tumors
REFERENCE :
   NCIMAV National Cancer Institute, Monograph.  (U.S. Government Printing
   Office, Supt. of Documents, Washington, DC 20402)  No.1-    1959-
   Volume(issue)/page/year: 51,103,1979
 
                            *** END OF RECORD ***