*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : RN8763000
CHEMICAL NAME           : 7-Oxabicyclo(4.1.0)heptane-2-propionic acid,
                          alpha-(2-aminopropionamido)-5-oxo-, stereoisomer
CAS REGISTRY NUMBER     : 29393-20-2
OTHER CAS REGISTRY NOS. : 1395-22-8
LAST UPDATED            : 198910
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C12-H18-N2-O5
MOLECULAR WEIGHT        : 270.32
WISWESSER LINE NOTATION : T36 BO DVTJ G1YVQMVYZ1
COMPOUND DESCRIPTOR     : Mutagen
SYNONYMS/TRADE NAMES :
   * N-L-Alanyl-3-(5-oxo-7-oxabicyclo(4.1.0)hept-2-yl)-L-alanine
   *   alpha-((2-Amino-1-oxopropyl)amino)-5-oxo-7-oxabicyclo(4.1.0)heptane-2-pr
     opanoic acid
   * alpha-(2-Aminopropionamido)-5-oxo-7-oxabicyclo(4.1.0)heptane-2-propionic  
   acid
   * Antibiotic KM 208
   * Bacillin
   * Bacilysin
   * KM-208
   * Tetaine
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 450 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85GDA2 "CRC Handbook of Antibiotic Compounds," Vols.1- ,  Berdy, J., Boca
   Raton, FL, CRC Press, 1980-  Volume(issue)/page/year: 4(1),221,1980
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : DNA inhibition
TEST SYSTEM             : Human HeLa cell
DOSE/DURATION           : 320 umol/L
REFERENCE :
   BBACAQ Biochimica et Biophysica Acta.  (Elsevier Science Pub. B.V., POB 211,
   1000 AE Amsterdam, Netherlands)  V.1-    1947- Volume(issue)/page/year:
   825,199,1985
 
TYPE OF TEST            : Mutation test systems - not otherwise specified
TEST SYSTEM             : Human HeLa cell
DOSE/DURATION           : 150 umol/L
REFERENCE :
   BBACAQ Biochimica et Biophysica Acta.  (Elsevier Science Pub. B.V., POB 211,
   1000 AE Amsterdam, Netherlands)  V.1-    1947- Volume(issue)/page/year:
   825,199,1985
 
                            *** END OF RECORD ***