*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : RO0238000
CHEMICAL NAME           : 1-Oxa-3,8-diazaspiro(4.5)decan-2-one,
                          8-(2,6-diamino-4-pyrimidinyl)-, 1'-oxide,
                          hydrochloride, hydrate
CAS REGISTRY NUMBER     : 83540-21-0
LAST UPDATED            : 199112
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C11-H16-N6-O3.Cl-H.H2-O
MOLECULAR WEIGHT        : 334.81
WISWESSER LINE NOTATION : T6N DXTJ A- DT6N CNJ AO BZ FZ& D-& DT5MVOX EHJ &GH
                          &QH
COMPOUND DESCRIPTOR     : Drug
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >3 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   BCFAAI Bollettino Chimico Farmaceutico.  (Societa Editoriale Farmaceutica,
   Via Ausonio 12, 20123 Milan, Italy)  V.33-    1894- Volume(issue)/page/year:
   121,16,1982
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 729 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   BCFAAI Bollettino Chimico Farmaceutico.  (Societa Editoriale Farmaceutica,
   Via Ausonio 12, 20123 Milan, Italy)  V.33-    1894- Volume(issue)/page/year:
   121,16,1982
 
                            *** END OF RECORD ***