*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : RO0548600 CHEMICAL NAME : 1,3,4-Oxadiazol-2-amine, 5-phenyl-, monohydrochloride CAS REGISTRY NUMBER : 1905-75-5 LAST UPDATED : 199203 DATA ITEMS CITED : 3 MOLECULAR FORMULA : C8-H7-N3-O.Cl-H MOLECULAR WEIGHT : 197.64 COMPOUND DESCRIPTOR : Drug SYNONYMS/TRADE NAMES : * 2-Amino-5-phenyl-1,3,4-oxadiazole hydrochloride * delta(sup 2)-1,3,4-Oxadiazoline, 5-imino-2-phenyl-, monohydrochloride * 5-Phenyl-1,3,4-oxadiazol-2-amine hydrochloride * SQ 4573 *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 440 mg/kg TOXIC EFFECTS : Behavioral - altered sleep time (including change in righting reflex) Behavioral - changes in motor activity (specific assay) REFERENCE : TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 3,726,1961 TYPE OF TEST : LD - Lethal dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Primate - monkey DOSE/DURATION : >400 mg/kg TOXIC EFFECTS : Behavioral - altered sleep time (including change in righting reflex) Behavioral - changes in motor activity (specific assay) REFERENCE : TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 3,726,1961 TYPE OF TEST : LD - Lethal dose ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Primate - monkey DOSE/DURATION : >60 mg/kg TOXIC EFFECTS : Behavioral - altered sleep time (including change in righting reflex) Behavioral - changes in motor activity (specific assay) REFERENCE : TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 3,726,1961 *** END OF RECORD ***