*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : RO0620000 CHEMICAL NAME : 1,3,4-Oxadiazole, 2-amino-5-phenyl- CAS REGISTRY NUMBER : 1612-76-6 LAST UPDATED : 199009 DATA ITEMS CITED : 2 MOLECULAR FORMULA : C8-H7-N3-O MOLECULAR WEIGHT : 161.18 WISWESSER LINE NOTATION : T5NN DOJ CZ ER COMPOUND DESCRIPTOR : Drug SYNONYMS/TRADE NAMES : * 2-Amino-5-phenyl-1,3,4-oxadiazole * 5-Amino-2-phenyl-1,3,4-oxadiazole * 2-Fenil-5-amino-1,3,4-ossadiazolo *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 300 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 9,478,1966 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 219 mg/kg TOXIC EFFECTS : Peripheral Nerve and Sensation - flaccid paralysis without anesthesia (usually neuromuscular blockage) Behavioral - changes in motor activity (specific assay) Behavioral - muscle weakness REFERENCE : FRPSAX Farmaco, Edizione Scientifica. (Casella Postale 227, 27100 Pavia, Italy) V.8-43 1953-88 For publisher information, see FRMCE8 Volume(issue)/page/year: 13,629,1958 *** END OF RECORD ***