*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : RO0685000
CHEMICAL NAME           : 1,2,4-Oxadiazole,
                          5-((2-(dibutylamino)ethyl)amino)-3-phenyl-,
                          hydrochloride
CAS REGISTRY NUMBER     : 56974-46-0
LAST UPDATED            : 199512
DATA ITEMS CITED        : 4
MOLECULAR FORMULA       : C18-H28-N4-O.Cl-H
MOLECULAR WEIGHT        : 352.96
WISWESSER LINE NOTATION : T5NO DNJ CM2N4&4 ER &GH
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Adrevil
   * Butalamine hydrochloride
   * 5-((2-(Dibutylamino)-ethyl)amino)-3-phenyl-1,2,4-oxadiazole hydrochloride
   * N,N-Dibutyl-N'-(3-phenyl-1,2,4-oxadiazol-5-yl)-1,2-ethanediamine  
   hydrochloride
   * 1,2-Ethanediamine, N,N'-dibutyl-N'-(3-phenyl-1,2,4-oxadiazol-5-yl)-,  
   monohydrochloride
   * Hemotrope
   * LA 1221
   * 3-Phenyl-5-(dibutylaminoethylamino)-1,2,4-oxadiazole hydrochloride
   * Surheme
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1600 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   THERAP Therapie.  (Doin, Editeurs, 8, Place de l'Odeon, F-75006 Paris,
   France)  V.1-    1946-  Volume(issue)/page/year: 24,745,1969
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 625 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   THERAP Therapie.  (Doin, Editeurs, 8, Place de l'Odeon, F-75006 Paris,
   France)  V.1-    1946-  Volume(issue)/page/year: 24,745,1969
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 2500 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   THERAP Therapie.  (Doin, Editeurs, 8, Place de l'Odeon, F-75006 Paris,
   France)  V.1-    1946-  Volume(issue)/page/year: 24,745,1969
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 43 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   THERAP Therapie.  (Doin, Editeurs, 8, Place de l'Odeon, F-75006 Paris,
   France)  V.1-    1946-  Volume(issue)/page/year: 24,745,1969
 
                            *** END OF RECORD ***