*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : RO0811300 CHEMICAL NAME : 1,3,4-Oxadiazole, 2-phenyl- CAS REGISTRY NUMBER : 825-56-9 BEILSTEIN REFERENCE NO. : 0118804 REFERENCE : 4-27-00-07140 (Beilstein Handbook Reference) LAST UPDATED : 199612 DATA ITEMS CITED : 2 MOLECULAR FORMULA : C8-H6-N2-O MOLECULAR WEIGHT : 146.16 WISWESSER LINE NOTATION : T5NN DOJ CR COMPOUND DESCRIPTOR : Drug SYNONYMS/TRADE NAMES : * 2-Fenil-1,3,4-ossadiazolo * 2-Phenyl-1,3,4-oxadiazole *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 440 mg/kg TOXIC EFFECTS : Behavioral - anticonvulsant Behavioral - somnolence (general depressed activity) REFERENCE : AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 121,443,1959 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 387 mg/kg TOXIC EFFECTS : Behavioral - altered sleep time (including change in righting reflex) Behavioral - changes in motor activity (specific assay) Behavioral - muscle weakness REFERENCE : FRPSAX Farmaco, Edizione Scientifica. (Casella Postale 227, 27100 Pavia, Italy) V.8-43 1953-88 For publisher information, see FRMCE8 Volume(issue)/page/year: 13,629,1958 *** END OF RECORD ***