*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : RO0833900
CHEMICAL NAME           : 1,3,4-Oxadiazole-2(3H)-thione,
                          5-(((2-methyl-4-quinazolinyl)oxy)methyl)-3-(4-
                          morpholinylmethyl)-
CAS REGISTRY NUMBER     : 96548-00-4
BEILSTEIN REFERENCE NO. : 5645241
LAST UPDATED            : 199612
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C17-H19-N5-O3-S
MOLECULAR WEIGHT        : 373.47
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   *   5-(((2-Methyl-4-quinazolinyl)oxy)methyl)-3-(4-morpholinylmethyl)-1,3,4-o
     xadiazole-2(3H)-thione
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 825 mg/kg
TOXIC EFFECTS :
   Behavioral - excitement
   Nutritional and Gross Metabolic - body temperature decrease
   Biochemical - Metabolism (Intermediary) - effect on inflammation or
   mediation of inflammation
REFERENCE :
   IJSBDB Indian Journal of Chemistry, Section B: Organic Chemistry, Including
   Medicinal Chemistry. (Publications & Information Directorate, Council of
   Scientific and Industrial Research (CSIR), Hillside Rd., New Delhi 110 012,
   India)  V.14B-    1976-  Volume(issue)/page/year: 24,78,1985
 
                            *** END OF RECORD ***