*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : RO4555000
CHEMICAL NAME           : Oxamic acid, (2-amino-2-carboxyethyl)-, L-
CAS REGISTRY NUMBER     : 5302-45-4
BEILSTEIN REFERENCE NO. : 2259036
LAST UPDATED            : 199612
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C5-H8-N2-O5
MOLECULAR WEIGHT        : 176.15
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * L-Alanine, 3-((carboxycarbonyl)amino)-
   * BOAA
   * 3-((Carboxycarbonyl)amino)-L-alanine
   * Dencichin
   * Dencichine
   * L-Dencichin
   * Neurotoxin (Lathyrus sativus)
   * L-3-Oxalylamino-2-aminopropionic acid
   * Ox-Dapro
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 301 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - ataxia
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   48,1,1979
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Primate - monkey
DOSE/DURATION           : 2006 mg/kg
TOXIC EFFECTS :
   Behavioral - tremor
   Behavioral - convulsions or effect on seizure threshold
   Gastrointestinal - hypermotility, diarrhea
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   47,135,1979
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Unreported
SPECIES OBSERVED        : Mammal - species unspecified
DOSE/DURATION           : 1043 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   CTYAD8 Zhongcaoyao.  Chinese Traditional and Herbal Medicine.  (China
   International Book Trading Corp., POB 2820, Beijing, Peop. Rep. China) V.11-
      1980-  Volume(issue)/page/year: 17,274,1986
 
                            *** END OF RECORD ***