*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : RP3433000
CHEMICAL NAME           : 1,2-Oxaphospholan-3-ol,
                          2-(dimethylamino)-3,5,5-trimethyl-, 2-oxide, cis-
CAS REGISTRY NUMBER     : 66830-78-2
LAST UPDATED            : 198903
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C8-H18-N-O3-P
MOLECULAR WEIGHT        : 207.24
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * cis-2-(Dimethylamino)-3,5,5-trimethyl-1,2-oxaphospholan-3-ol 2-oxide
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 4500 mg/kg
TOXIC EFFECTS :
   Behavioral - changes in motor activity (specific assay)
   Lungs, Thorax, or Respiration - respiratory depression
   Nutritional and Gross Metabolic - body temperature decrease
REFERENCE :
   PCJOAU Pharmaceutical Chemistry Journal (English Translation).  Translation
   of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013)  No.1-
   1967-  Volume(issue)/page/year: 21,91,1987
 
                            *** END OF RECORD ***