*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : RP3850000
CHEMICAL NAME           : 6-Oxa-3-thiabicyclo(3.1.0)hexane 3,3-dioxide
CAS REGISTRY NUMBER     : 4509-11-9
BEILSTEIN REFERENCE NO. : 0113462
REFERENCE               : 4-19-00-00111 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C4-H6-O3-S
MOLECULAR WEIGHT        : 134.16
WISWESSER LINE NOTATION : T35 BO ESWTJ
COMPOUND DESCRIPTOR     : Tumorigen
                          Drug
SYNONYMS/TRADE NAMES :
   * 3,4-Epoxysulfolane
   * 2,3-Epoxytetramethylene sulfone
   * Tetrahydro-3,4-epoxythiophene 1,1-dioxide
   * Thiophene, tetrahydro-3,4-epoxy-, 1,1-dioxide
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 5500 mg/kg
TOXIC EFFECTS :
   Biochemical - Metabolism (Intermediary) - effect on inflammation or
   mediation of inflammation
REFERENCE :
   RPTOAN Russian Pharmacology and Toxicology (English Translation).
   Translation of FATOAO.  (Euromed Pub., 33, Woodlands Rd., Surbiton, Surrey,
   UK)  V.30-    1967-  Volume(issue)/page/year: 41,257,1978
 
                          ** TUMORIGENIC DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 88 mg/kg/22W-I
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Tumorigenic - tumors at site of application
REFERENCE :
   JNCIAM Journal of the National Cancer Institute.  (Washington, DC)  V.1-60,
   1940-78.  For publisher information, see JJIND8.  Volume(issue)/page/year:
   46,143,1971
 
                            *** END OF RECORD ***