*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : RP5948000
CHEMICAL NAME           : 2H-1,3,2-Oxazaphosphorine,
                          2-(bis(2-chloroethyl)amino)tetrahydro-5,5-dimethyl-,
                          2-oxide
CAS REGISTRY NUMBER     : 22089-27-6
BEILSTEIN REFERENCE NO. : 0984472
LAST UPDATED            : 199612
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C9-H19-Cl2-N2-O2-P
MOLECULAR WEIGHT        : 289.17
WISWESSER LINE NOTATION : T6MPOTJ BO BN2G2G E1 E1
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * B 707
   *   N,N-Bis(2-chlorethyl)tetrahydro-5,5-dimethyl-2H-1,3,2-oxazaphosphorin-2-
     amine 2-oxide
   * 5,5-Dimethylcyclophosphamide
   *   Tetrahydro-2-(bis(2-chloroethyl)amino)-5,5-dimethyl-2H-1,3,2-oxazaphosph
     orine 2-oxide
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 400 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 11,143,1961
 
                            *** END OF RECORD ***