*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : RP6040000
CHEMICAL NAME           : 2H-1,3,2-Oxazaphosphorine,
                          3-(2-chloroethyl)-2-(2-chloroethyl)amino-4-hydroxytet
                          rahydro-
CAS REGISTRY NUMBER     : 67292-64-2
LAST UPDATED            : 199109
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C7-H15-Cl2-N2-O3-P
MOLECULAR WEIGHT        : 277.11
WISWESSER LINE NOTATION : T6NPOTJ A2G BM2G FQ
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   *   3-(2-Chloroethyl)-2-(2-chloroethyl)amino-4-hydroxytetrahydro-2H-1,3,2-ox
     azaphosphorine
   * 4-Hydroxyifosfamide
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 200 mg/kg
TOXIC EFFECTS :
   Tumorigenic - active as anti-cancer agent
REFERENCE :
   CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
   Sts., Philadelphia, PA 19106)  V.1-    1941-  Volume(issue)/page/year:
   36,2278,1976
 
                            *** END OF RECORD ***