*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : RP6154000
CHEMICAL NAME           : 2H-1,3,2-Oxazaphosphorine,
                          tetrahydro-2-(bis(2-chloroethyl)amino)-4-methyl-,
                          2-oxide, (+)-cis- (2S,4S)-
CAS REGISTRY NUMBER     : 61520-80-7
LAST UPDATED            : 199012
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C8-H17-Cl2-N2-O2-P
MOLECULAR WEIGHT        : 275.14
WISWESSER LINE NOTATION : T6MPOTJ BO BN2G2G F1 -C
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   *   (+)-cis-2-(Bis(2-chloroethyl)amino)-4-methyltetrahydro-2H-1,3,2-oxazapho
     sphorine 2-oxide
   * (+)-cis-4-Methylcyclophosphamide
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 225 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   CBINA8 Chemico-Biological Interactions.  (Elsevier Scientific Pub. Ireland
   Ltd., POB 85, Limerick, Ireland)  V.1-    1969-  Volume(issue)/page/year:
   18,47,1977
 
                            *** END OF RECORD ***