*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : RQ2280000
CHEMICAL NAME           : 2-Oxazolidinethione, 5-vinyl-, (R)-
CAS REGISTRY NUMBER     : 1072-93-1
LAST UPDATED            : 199403
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C5-H7-N-O-S
MOLECULAR WEIGHT        : 129.19
WISWESSER LINE NOTATION : T5MYOTJ BUS D1U1
COMPOUND DESCRIPTOR     : Reproductive Effector
SYNONYMS/TRADE NAMES :
   * BA 51-090278
   * (R)-5-Ethenyl-2-oxazolidinethione
   * D-Goitrin
   * (R)-Goitrin
   * 2-Oxazolidinethione, 5-ethenyl-, (R)-
   * R-5-Vinyl-2-oxazolidinethione
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Unreported
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1260 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JAFCAU Journal of Agricultural and Food Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB 57136, West End Stn., Washington, DC
   20037)  V.1-    1953-  Volume(issue)/page/year: 17,483,1969
 
                 ** OTHER MULTIPLE DOSE TOXICITY DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 120 mg/kg/4D-I
TOXIC EFFECTS :
   Liver - changes in liver weight
   Endocrine - changes in thyroid weight
   Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol)
REFERENCE :
   FCTOD7 Food and Chemical Toxicology.  (Pergamon Press Inc., Maxwell House,
   Fairview Park, Elmsford, NY 10523)  V.20-    1982- Volume(issue)/page/year:
   20,279,1982
 
                          ** REPRODUCTIVE DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 200 mg/kg
SEX/DURATION            : female 8-9 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death,
   e.g., stunted fetus)
REFERENCE :
   FCTXAV Food and Cosmetics Toxicology.  (London, UK)  V.1-19, 1963-81.  For
   publisher information, see FCTOD7.  Volume(issue)/page/year: 18,159,1980
 
                            *** END OF RECORD ***