*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : RR6475000
CHEMICAL NAME           : Oxyacanthan-12'-ol, 6,6',7-trimethoxy-2,2'-dimethyl-
CAS REGISTRY NUMBER     : 548-40-3
OTHER CAS REGISTRY NOS. : 62018-86-4
BEILSTEIN REFERENCE NO. : 0078853
LAST UPDATED            : 199612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C37-H40-N2-O6
MOLECULAR WEIGHT        : 608.79
COMPOUND DESCRIPTOR     : Drug
                          Natural Product
SYNONYMS/TRADE NAMES :
   * N-Methylocoteamine
   * N-Methylsepeerine
   * Oxyacanthine
   * (+)-Oxyacanthine
   * 6,6',7-Trimethoxy-2,2'-dimethyl-oxyacanthan-12'-ol
   * Vinetine
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 250 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NCNSA6 National Academy of Sciences, National Research Council,
   Chemical-Biological Coordination Center, Review.  (Washington, DC)
   Volume(issue)/page/year: 5,17,1953
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 50 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   CPBTAL Chemical and Pharmaceutical Bulletin.  (Japan Pub. Trading Co., USA,
   1255 Howard St., San Francisco, CA 94103)  V.6-    1958-
   Volume(issue)/page/year: 24,2413,1976
 
                            *** END OF RECORD ***