*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : RT4735000 CHEMICAL NAME : Palmitic acid, alpha-ester with D-threo-(-)-2,2-dichloro-N-(beta-hydroxy-alpha- (hydroxymethyl)-p-nitrophenethyl)acetamide CAS REGISTRY NUMBER : 530-43-8 BEILSTEIN REFERENCE NO. : 2826438 REFERENCE : 4-13-00-02753 (Beilstein Handbook Reference) LAST UPDATED : 199612 DATA ITEMS CITED : 3 MOLECULAR FORMULA : C27-H42-Cl2-N2-O6 MOLECULAR WEIGHT : 561.61 WISWESSER LINE NOTATION : WNR DYQY1OV15&MVYGG COMPOUND DESCRIPTOR : Reproductive Effector SYNONYMS/TRADE NAMES : * CAP-P * CAP-palmitate * Chloramphenicol monopalmitate * Chloramphenicol palmitate * Chloramphenicol alpha-palmitate * Chloramphenicol palmitate (ester) * Chloromycetin palmitate * Detreopal *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 2640 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,248,1982 ** REPRODUCTIVE DATA ** TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rabbit DOSE : 1200 mg/kg SEX/DURATION : female 7-12 day(s) after conception TOXIC EFFECTS : Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus) REFERENCE : VHAGAS Verhandlungen der Anatomischen Gesellschaft. (VEB Gustav Fischer Verlag, Postfach 176, Jena, DDR-6900, Ger. Dem. Rep.) V.1- 1887- Volume(issue)/page/year: 71,623,1977 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X2340 No. of Facilities: 79 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 318 (estimated) No. of Female Employees: 132 (estimated) *** END OF RECORD ***