*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : RT4735000
CHEMICAL NAME           : Palmitic acid, alpha-ester with
                          D-threo-(-)-2,2-dichloro-N-(beta-hydroxy-alpha-
                          (hydroxymethyl)-p-nitrophenethyl)acetamide
CAS REGISTRY NUMBER     : 530-43-8
BEILSTEIN REFERENCE NO. : 2826438
REFERENCE               : 4-13-00-02753 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C27-H42-Cl2-N2-O6
MOLECULAR WEIGHT        : 561.61
WISWESSER LINE NOTATION : WNR DYQY1OV15&MVYGG
COMPOUND DESCRIPTOR     : Reproductive Effector
SYNONYMS/TRADE NAMES :
   * CAP-P
   * CAP-palmitate
   * Chloramphenicol monopalmitate
   * Chloramphenicol palmitate
   * Chloramphenicol alpha-palmitate
   * Chloramphenicol palmitate (ester)
   * Chloromycetin palmitate
   * Detreopal
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 2640 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NIIRDN Drugs in Japan (Ethical Drugs).  (Yakugyo Jiho Co., Ltd., Tokyo,
   Japan)  Volume(issue)/page/year: 6,248,1982
 
                          ** REPRODUCTIVE DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rabbit
DOSE                    : 1200 mg/kg
SEX/DURATION            : female 7-12 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Fertility - post-implantation mortality (e.g. dead and/or
   resorbed implants per total number of implants)
   Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death,
   e.g., stunted fetus)
REFERENCE :
   VHAGAS Verhandlungen der Anatomischen Gesellschaft.  (VEB Gustav Fischer
   Verlag, Postfach 176, Jena, DDR-6900, Ger. Dem. Rep.)  V.1-    1887-
   Volume(issue)/page/year: 71,623,1977

         *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
   NOES - National Occupational Exposure Survey (1983)
     NOES Hazard Code - X2340
       No. of Facilities: 79 (estimated)
       No. of Industries: 1
       No. of Occupations: 1
       No. of Employees: 318 (estimated)
       No. of Female Employees: 132 (estimated)

 
                            *** END OF RECORD ***