*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : RU3940000 CHEMICAL NAME : Pantopon CAS REGISTRY NUMBER : 8002-76-4 LAST UPDATED : 198910 DATA ITEMS CITED : 2 COMPOUND DESCRIPTOR : Drug Human SYNONYMS/TRADE NAMES : * Concentrated opium * Omnopon * Omnopone * Pantopan * Pantopium * Papaveretum * Tetrapon *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Human - woman DOSE/DURATION : 2400 ug/kg/36H-I TOXIC EFFECTS : Lungs, Thorax, or Respiration - respiratory depression REFERENCE : BMJOAE British Medical Journal. (British Medical Assoc., BMA House, Tavistock Sq., London WC1H 9JR, UK) V.1- 1857- Volume(issue)/page/year: 1,211,1959 TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 450 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : AEPPAE Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. (Berlin, Ger.) V.110-253, 1925-66. For publisher information, see NSAPCC. Volume(issue)/page/year: 197,636,1941 *** END OF RECORD ***