*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : RV0350000
CHEMICAL NAME : Paraffin
CAS REGISTRY NUMBER : 8002-74-2
LAST UPDATED : 199712
DATA ITEMS CITED : 26
COMPOUND DESCRIPTOR : Tumorigen
Primary Irritant
SYNONYMS/TRADE NAMES :
* Paraffin wax fume
*** HEALTH HAZARD DATA ***
** SKIN/EYE IRRITATION DATA **
TYPE OF TEST : Standard Draize test
ROUTE OF EXPOSURE : Administration onto the skin
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : 500 mg/24H
REACTION SEVERITY : Mild
REFERENCE :
JACTDZ Journal of the American College of Toxicology. (Mary Ann Liebert,
Inc., 1651 Third Ave., New York, NY 10128) V.1-12, 1982-1993. Discontinued.
Volume(issue)/page/year: 3(3),43,1984
TYPE OF TEST : Standard Draize test
ROUTE OF EXPOSURE : Administration into the eye
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : 100 mg/24H
REACTION SEVERITY : Mild
REFERENCE :
JACTDZ Journal of the American College of Toxicology. (Mary Ann Liebert,
Inc., 1651 Third Ave., New York, NY 10128) V.1-12, 1982-1993. Discontinued.
Volume(issue)/page/year: 3(3),43,1984
** TUMORIGENIC DATA **
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Implant
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 120 mg/kg
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria
Kidney, Ureter, Bladder - tumors
REFERENCE :
CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year:
33,1225,1973
TYPE OF TEST : TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE : Implant
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 640 mg/kg
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria
Kidney, Ureter, Bladder - tumors
REFERENCE :
BJCAAI British Journal of Cancer. (Macmillan Press Ltd., Houndmills,
Basingstoke, Hants. RG21 2XS, UK) V.1- 1947- Volume(issue)/page/year:
17,127,1963
TYPE OF TEST : TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE : Implant
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 660 mg/kg
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria
Kidney, Ureter, Bladder - tumors
REFERENCE :
CALEDQ Cancer Letters (Shannon, Ireland). (Elsevier Scientific Pub. Ireland
Ltd., POB 85, Limerick, Ireland) V.1- 1975- Volume(issue)/page/year:
6,21,1979
TYPE OF TEST : TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE : Implant
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 560 mg/kg
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria
Lungs, Thorax, or Respiration - tumors
Kidney, Ureter, Bladder - tumors
REFERENCE :
BJURAN British Journal of Urology. (Longman Group Ltd., POB 11318,
Birmingham, AL 35202) V.1- 1929- Volume(issue)/page/year: 36,225,1964
*** REVIEWS ***
ACGIH TLV-TWA 2 mg/m3, vapor
DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices
(BEIs) booklet issues by American Conference of Governmental Industrial
Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year:
TLV/BEI,1997
TOXICOLOGY REVIEW
JNCIAM Journal of the National Cancer Institute. (Washington, DC) V.1-60,
1940-78. For publisher information, see JJIND8. Volume(issue)/page/year:
52,1685,1974
TOXICOLOGY REVIEW
ADCSAJ Advances in Chemistry Series. (American Chemical Soc., Distribution
Office Dept. 223, POB 57136, West End Stn., Washington, DC 20037) No.1-
1950- Volume(issue)/page/year: 13,271,1970
*** OCCUPATIONAL EXPOSURE LIMITS ***
OEL-AUSTRALIA:TWA 2 mg/m3 (fume) JAN 1993
OEL-BELGIUM:TWA 2 mg/m3 (fume) JAN 1993
OEL-DENMARK:TWA 2 mg/m3 (fume) JAN 1993
OEL-FINLAND:TWA 1 mg/m3 (fume) JAN 1993
OEL-FRANCE:TWA 2 mg/m3 (fume) JAN 1993
OEL-THE NETHERLANDS:TWA 2 mg/m3 (fume) JAN 1993
OEL-SWITZERLAND:TWA 2 mg/m3 (fume) JAN 1993
OEL-UNITED KINGDOM:TWA 2 mg/m3;STEL 6 mg/m3 (fume) JAN 1993
OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV
OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV
*** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***
NIOSH RECOMMENDED EXPOSURE LEVEL (REL) :
NIOSH REL TO PARAFFIN WAX FUME-air:10H TWA 2 mg/m3
REFERENCE :
NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of
Health, Education, and Welfare, Reports and Memoranda.
Volume(issue)/page/year: DHHS #92-100,1992
NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
NOHS - National Occupational Hazard Survey (1974)
NOHS Hazard Code - M0600
No. of Facilities: 42016 (estimated)
No. of Industries: 248
No. of Occupations: 168
No. of Employees: 485821 (estimated)
NOES - National Occupational Exposure Survey (1983)
NOES Hazard Code - M0600
No. of Facilities: 31266 (estimated)
No. of Industries: 237
No. of Occupations: 159
No. of Employees: 703496 (estimated)
No. of Female Employees: 215598 (estimated)
*** STATUS IN U.S. ***
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA Section 8(d) unpublished health/safety studies
EPA TSCA Section 8(e) Risk Notification, 8EHQ-0892-9311
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JUNE 1998
*** END OF RECORD ***