*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : RV9380000 CHEMICAL NAME : Paraxanthine CAS REGISTRY NUMBER : 611-59-6 BEILSTEIN REFERENCE NO. : 0197907 REFERENCE : 5-26-13-00554 (Beilstein Handbook Reference) LAST UPDATED : 199612 DATA ITEMS CITED : 4 MOLECULAR FORMULA : C7-H8-N4-O2 MOLECULAR WEIGHT : 180.19 WISWESSER LINE NOTATION : T56 BN DN FMVNVJ B1 H1 COMPOUND DESCRIPTOR : Mutagen Reproductive Effector SYNONYMS/TRADE NAMES : * 3,7-Dihydro-1,7-dimethyl-1H-purine-2,6-dione * 1,7-Dimethylxanthine * 1H-Purine-2,6-dione, 3,7-dihydro-1,7-dimethyl- *** HEALTH HAZARD DATA *** ** REPRODUCTIVE DATA ** TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE : 600 mg/kg SEX/DURATION : female 11-12 day(s) after conception TOXIC EFFECTS : Reproductive - Specific Developmental Abnormalities - eye/ear Reproductive - Specific Developmental Abnormalities - craniofacial (including nose and tongue) Reproductive - Specific Developmental Abnormalities - musculoskeletal system REFERENCE : TJADAB Teratology, The International Journal of Abnormal Development. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.1- 1968- Volume(issue)/page/year: 34,279,1986 ** MUTATION DATA ** TYPE OF TEST : Mutation in microorganisms TEST SYSTEM : Bacteria - Escherichia coli DOSE/DURATION : 150 mg/L REFERENCE : CSHSAZ Cold Spring Harbor Symposia on Quantitative Biology. (Cold Spring Harbor Laboratory, POB 100, Cold Spring Harbor, NY 11724) V.1- 1933- Volume(issue)/page/year: 16,337,1952 TYPE OF TEST : Unscheduled DNA synthesis TEST SYSTEM : Human Cells - not otherwise specified DOSE/DURATION : 1 mmol/L REFERENCE : BIOJAU Biophysical Journal. (Rockefeller Univ. Press, 1230 York Ave., New York, NY 10021) V.1- 1960- Volume(issue)/page/year: 35,665,1981 TYPE OF TEST : DNA inhibition TEST SYSTEM : Human Cells - not otherwise specified DOSE/DURATION : 4 mmol/L REFERENCE : BIOJAU Biophysical Journal. (Rockefeller Univ. Press, 1230 York Ave., New York, NY 10021) V.1- 1960- Volume(issue)/page/year: 35,665,1981 *** END OF RECORD ***